Publication

Virucidal compounds and use thereof

Related publications (28)

Covalent and Noncovalent Conjugation of Degradable Polymer Nanoparticles to T Lymphocytes

Cells are attractive as carriers that can help to enhance control over the biodistribution of polymer nanomedicines. One strategy to use cells as carriers is based on the cell surface immobilization of the nanoparticle cargo. While a range of strategies ca ...

American Chemical Society2021

Hydrogenation of a Benzene-Toluene Mixture Using Metal Nanoparticles Stabilized by a Hyper-Crosslinked Aromatic Polymer

Lioubov Kiwi

Hydrogenation of aromatic compounds is a widely used catalytic process in modern industry. Selective hydrogenation of benzene (BZ)-toluene (TL) mixtures is an important industrial process as it allows the purification of BZ for further synthetic purposes. ...

WILEY-V C H VERLAG GMBH2021

The fragmentation mechanism of gold nanoparticles in water under femtosecond laser irradiation

Marcel Drabbels, Ulrich Lorenz, Pavel Olshin, Gabriele Bongiovanni, Jonathan Mark Voss, Chengcheng Yan

Plasmonic nanoparticles in aqueous solution have long been known to fragment under irradiation with intense ultrafast laser pulses, creating progeny particles with diameters of a few nanometers. However, the mechanism of this process is still intensely deb ...

2021

Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo

Francesco Stellacci, Paulo Henrique Jacob Silva, Özgün Kocabiyik, Valeria Cagno, Yong Zhu, Chiara Medaglia

Influenza is one of the most widespread viral infections worldwide and represents a major public health problem. The risk that one of the next pandemics is caused by an influenza strain is high. It is important to develop broad-spectrum influenza antiviral ...

2020

Contact networks across ages: computational analysis of epidemiological dynamics

Gianrocco Lazzari

For decades mathematical modeling in epidemiology has helped understanding the dynamics of infectious diseases, as well as describe possible intervention scenarios to prevent and control them. However, such models were relying on several assumptions, such ...

EPFL2020

Sulfonated Nanomaterials with Broad-Spectrum Antiviral Activity Extending beyond Heparan Sulfate-Dependent Viruses

Francesco Stellacci, Valeria Cagno, Matteo Gasbarri, Chiara Medaglia

Viral infections are among the main causes of death worldwide, and we lack antivirals for the majority of viruses. Heparin-like sulfated or sulfonated compounds have been known for decades for their ability to prevent infection by heparan sulfate proteogly ...

AMER SOC MICROBIOLOGY2020

Virucidal nanoparticles and use thereof against influenza virus

Francesco Stellacci, Özgün Kocabiyik, Valeria Cagno

The invention relates to virucidal nanoparticles comprising a trisaccharide moiety and use thereof against influenza virus. ...

2020

Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation

Suliana Manley, Christian Sieben

Influenza A virus (IAV) binds its host cell using the major viral surface protein hemagglutinin (HA). HA recognizes sialic acid, a plasma membrane glycan that functions as the specific primary attachment factor (AF). Since sialic acid alone cannot fulfill ...

2020