Blood virosphere in febrile Tanzanian children

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The bacterial ecosystem is naturally balanced by viruses known as bacteriophages. Accordingly, they represent an emerging adjuvant to antibiotics to fight bacterial infections. However, the interaction of a single bacterium with bacteriophages remains poor ...

The global pandemic of SARS-CoV-2 has highlighted the necessity for innovative therapeutic solutions. This research presents a new formulation utilising the metal–organic framework MIL-101(Al)–NH2, which is loaded with hypericin, aimed at addressing viral ...

Evolutionary changes in the hepatitis B virus (HBV) genome could reflect its adaptation to host -induced selective pressure. Leveraging paired human exome and ultra -deep HBV genome-sequencing data from 567 affected individuals with chronic hepatitis B, we ...

The pathogenesis of HIV-1 infection is governed by a highly dynamic, time-dependent interaction between the host and the viral genome. In this study, we developed a novel systematic approach to assess the host-virus interaction, using average pairwise vira ...

Two years into the most significant infectious disease event of our generation, infections have populated every conversation and in-depth understanding of host-pathogen interactions has, perhaps, never been more important. In a successful return to in-pers ...

Background. The role of primary immunodeficiencies (PID) in susceptibility to sepsis remains unknown. It is unclear whether children with sepsis benefit from genetic investigations. We hypothesized that sepsis may represent the first manifestation of under ...

Blood virosphere in febrile Tanzanian children

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Monitoring of Single-Cell Bacterial Lysis by Phages Within Integrated Optical Traps

The potential of metal–organic framework MIL-101(Al)–NH2 in the forefront of antiviral protection of cells via interaction with SARS-CoV-2 spike RBD protein and their antibacterial action mediated with hypericin and photodynamic treatment

Joint host-pathogen genomic analysis identifies hepatitis B virus mutations associated with human NTCP and HLA class I variation

Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen

Meeting report - Cell dynamics: host-pathogen interface

Whole-exome Sequencing for the Identification of Rare Variants in Primary Immunodeficiency Genes in Children With Sepsis: A Prospective, Population-based Cohort Study