Publication

SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

Kai Johnsson, Luc Reymond, Alberto Schena
2015
Journal Articles

Abstract

Cell-permeable DNA stains are popular markers in live-cell imaging. Currently used DNA stains for live-cell imaging are either toxic, require illumination with blue light or are not compatible with super-resolution microscopy, thereby limiting their utility. Here we describe a far-red DNA stain, SiR–Hoechst, which displays minimal toxicity, is applicable in different cell types and tissues, and is compatible with super-resolution microscopy. The combination of these properties makes this probe a powerful tool for live-cell imaging.

Official source

https://infoscience.epfl.ch/entities/publication/fa85beb8-059b-4e86-ba91-44368dc4c6d3

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SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

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