Publication

A pan-cancer classification based on fmrp pathway activity that informs differential prognosis and therapeutic responses

Douglas Hanahan
2022
Patents

Abstract

The present invention relates to methods and compositions which provide a companion diagnostic for cancer therapy. A method for identifying and stratifying a patient or group of patients with cancer as (i) being high or low for FMRP activity, (ii) having a high or low risk prognosis, and/or (iii) being a responder or non-responder to cancer therapy, and/or (iv) having high or low immune cell infiltrated tumor.

Official source

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

A pan-cancer classification based on fmrp pathway activity that informs differential prognosis and therapeutic responses

Chat with Graph Search

Exploration and modulation of mechanical cues for enhanced cancer immunotherapy

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Development of cysteine cathepsin inhibitors combined with cell type-specific delivery for the treatment of B-cell lymphoma and solid tumors