Publication

Synchrotron spectromicroscopy for the life sciences: General considerations and special procedures

Giorgio Margaritondo
1997
Journal Articles

Abstract

The effort to apply synchrotron spectromicroscopy techniques to life science problems is definitely beyond the feasibility-test stage. Furthermore, the commissioning of ultrabright, third-generation soft-X-ray sources such as Elettra in Trieste or the advanced light source in Berkeley has boosted this effort, most notably in the areas of scanning and electron-imaging photoelectron spectromicroscopy. Besides producing research results, the effort also develops new procedures and finds solutions for new conceptual problems. We first briefly review the basic experimental techniques in this domain; then we discuss some specific experimental issues, such as the specimen preparation problems caused by peculiar features of the techniques, e.g., their surface sensitivity. Third, we briefly present conceptual considerations on the optimization of the data-taking procedures. Finally, we illustrate the applications in biology with a few specific research examples, and analyze the probable future developments in this area. (C) 1997 John Wiley & Sons, inc.

Official source

https://infoscience.epfl.ch/entities/publication/ee27cf3d-955c-419a-b6c0-07ac043c4d85

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Giorgio Margaritondo
1997
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/ee27cf3d-955c-419a-b6c0-07ac043c4d85

About this result

Related concepts (31)

Experimental psychology

Experimental psychology refers to work done by those who apply experimental methods to psychological study and the underlying processes. Experimental psychologists employ human participants and animal subjects to study a great many topics, including (among others) sensation & perception, memory, cognition, learning, motivation, emotion; developmental processes, social psychology, and the neural substrates of all of these.

Synchrotron light source

A synchrotron light source is a source of electromagnetic radiation (EM) usually produced by a storage ring, for scientific and technical purposes. First observed in synchrotrons, synchrotron light is now produced by storage rings and other specialized particle accelerators, typically accelerating electrons. Once the high-energy electron beam has been generated, it is directed into auxiliary components such as bending magnets and insertion devices (undulators or wigglers) in storage rings and free electron lasers.

Research question

A research question is "a question that a research project sets out to answer". Choosing a research question is an essential element of both quantitative and qualitative research. Investigation will require data collection and analysis, and the methodology for this will vary widely. Good research questions seek to improve knowledge on an important topic, and are usually narrow and specific. To form a research question, one must determine what type of study will be conducted such as a qualitative, quantitative, or mixed study.