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As a building physicis engineer specialized in daylighting and passive solar strategies for buildings, Marilyne Andersen provides an overview of her pioneering work in comfort and health implications of daylight, and on low-energy building technologies. With a clear interdisciplinary research focus at the interface between the domains of architectural design, building engineering and more fundamental science, she has opened new development and cooperation perspectives between fields otherwise as remote from design as photobiology, vision and eye-tracking research, and optics.