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Macroscale analogues(1-3) of microscopic spin systems offer direct insights into fundamental physical principles, thereby advancing our understanding of synchronization phenomena(4) and informing the design of novel classes of chiral metamaterials(5-7). Here we introduce hydrodynamic spin lattices (HSLs) of 'walking' droplets as a class of active spin systems with particle-wave coupling. HSLs reveal various non-equilibrium symmetry-breaking phenomena, including transitions from antiferromagnetic to ferromagnetic order that can be controlled by varying the lattice geometry and system rotation(8). Theoretical predictions based on a generalized Kuramoto model(4) derived from first principles rationalize our experimental observations, establishing HSLs as a versatile platform for exploring active phase oscillator dynamics. The tunability of HSLs suggests exciting directions for future research, from active spin-wave dynamics to hydrodynamic analogue computation and droplet-based topological insulators.