Publication

Lymphoma Chemotherapy: Hungry Macrophages Strike the Final Blow

Michele De Palma, Florent Philippe Maurice Duval
2019
Journal Articles

Abstract

Macrophages modulate tumor response to chemotherapy; in this issue, Lossos and colleagues show that high-dose alkylating agents instigate a synthetic lethal program in lymphoma cells that is independent of DNA damage and involves recruitment and priming of macrophages for antibody-mediated tumor phagocytosis. These fi ndings implicate chemotherapy-elicited macrophages as critical effectors of lymphoma clearance during biological therapy.

Official source

https://infoscience.epfl.ch/entities/publication/ec9526ec-2a4f-4cb4-97cf-37a4e37eb7eb

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Lymphoma Chemotherapy: Hungry Macrophages Strike the Final Blow

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