Development of a single-molecule approach to observe ubiquitination dynamics in defined chromatin states

Beat Fierz, Alexandra Teslenko
2021
Conference Papers

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Beat Fierz, Alexandra Teslenko
2021
Conference Papers

Official source

Related publications (3)

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Related publications (3)

Chromatin landscape at cis-regulatory elements orchestrates cell fate decisions in early embryogenesis

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The establishment of germ layers during early development is crucial for body formation. The Drosophila zygote serves as a model for investigating these transitions in relation to the chromatin landscape. However, the cellular heterogeneity of the blastode ...

Springer Science and Business Media LLC2025

Navigating the crowd: visualizing coordination between genome dynamics, structure, and transcription

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The eukaryotic genome is hierarchically structured yet highly dynamic. Regulating transcription in this environment demands a high level of coordination to permit many proteins to interact with chromatin fiber at appropriate sites in a timely manner. We de ...

2020

Common genetic variants associated with Parkinson's disease display widespread signature of epigenetic plasticity

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Parkinson disease (PD) is characterized by a pivotal progressive loss of substantia nigra dopaminergic neurons and aggregation of alpha-synuclein protein encoded by the SNCA gene. Genome-wide association studies identified almost 100 sequence variants link ...

Springer Nature2019