Publication

Attenuation of Cross-Peak Intensities in QUIET-BIRD-NOESY Experiments

Geoffrey Bodenhausen
1999
Journal Articles

Abstract

The buildup curves in QUIET-BIRD-NOESY expts., which are designed to isolate two-spin subsystems within macromols., are attenuated by transverse relaxation and evolution under homonuclear couplings during the bilinear rotation decoupling (BIRD) pulse sandwich. If the signals of both source and target spins are attenuated equally (uniform damping), this is readily accounted for by normalizing the cross peaks with respect to the diagonal peaks. However, unequal attenuation of source and target spins (differential damping) affects the initial buildup slopes and hence leads to apparent cross-relaxation rates that are significantly distorted from their true values. A simple method for recognizing this situation and extg. accurate cross-relaxation rates is presented. (c) 1999 Academic Press. [on SciFinder (R)]

Official source

https://infoscience.epfl.ch/entities/publication/ea4501b8-3024-46c7-b82b-472402c43b88

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Geoffrey Bodenhausen
1999
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/ea4501b8-3024-46c7-b82b-472402c43b88

About this result

Related concepts (28)

Two-dimensional nuclear magnetic resonance spectroscopy

Two-dimensional nuclear magnetic resonance spectroscopy (2D NMR) is a set of nuclear magnetic resonance spectroscopy (NMR) methods which give data plotted in a space defined by two frequency axes rather than one. Types of 2D NMR include correlation spectroscopy (COSY), J-spectroscopy, exchange spectroscopy (EXSY), and nuclear Overhauser effect spectroscopy (NOESY). Two-dimensional NMR spectra provide more information about a molecule than one-dimensional NMR spectra and are especially useful in determining the structure of a molecule, particularly for molecules that are too complicated to work with using one-dimensional NMR.

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In physics, the spin–spin relaxation is the mechanism by which Mxy, the transverse component of the magnetization vector, exponentially decays towards its equilibrium value in nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). It is characterized by the spin–spin relaxation time, known as T2, a time constant characterizing the signal decay. It is named in contrast to T1, the spin–lattice relaxation time.

Spin–lattice relaxation

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