Arrays of discrete cell culture microenvironments, methods of making such arrays and uses thereof

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Expansion and differentiation of antigen-experienced PD-1(+)TCF-1(+) stem-like CD8(+) T cells into effector cells is critical for the success of immunotherapies based on PD-1 blockade(1-4). Hashimoto et al. have shown that, in chronic infections, administr ...

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Advances in our understanding of the biology of stem cells and their niches have provided the necessary foundation to create in vitro complex self-organizing three-dimensional (3D) structures called organoids. While organoids represent a highly promising n ...

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Arrays of discrete cell culture microenvironments, methods of making such arrays and uses thereof

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PD-1-cis IL-2R agonism yields better effectors from stem-like CD8(+) T cells

Dissecting the role of biliary epithelial cells during non-alcoholic fatty liver disease progression

Molecular Regulation of Muscle Stem Cell Fate during Skeletal Muscle Regeneration and Aging

Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34(+) stromal cell subsets

p High-Throughput Single-Cell TCR-pMHC Dissociation Rate Measurements Performed by an Autonomous Microfluidic Cellular Processing Unit

Engineering next generation organoids through guided stem cell self-organisation

Intestinal stem cells differentiation and its application in cancer therapy

Systematic inference and comparison of multi-scale chromatin sub-compartments connects spatial organization to cell phenotypes

Defined matrices for epithelial organoid culture and disease modelling

Post-translational regulation of neuronal differentiation

Extracellular matrix requirements for gastrointestinal organoid cultures

The role and transcriptional regulation of FAM46A in adipocyte differentiation