Publications related to Coherent Anti-Stokes Raman Scattering Holography: Theory And Experiment

3D reconstruction of curvilinear one-dimensional objects viewed in transmission electron microscopy

To obtain a more complete understanding of material microstructure at the nanoscale and to gain profound insights into their properties, there is a growing need for more efficient and precise methods that can streamline the process of 3D imaging using a tr ...

EPFL2023

3-Dimensional Fluid and White Matter Suppression Magnetic Resonance Imaging Sequence Accelerated With Compressed Sensing Improves Multiple Sclerosis Cervical Spinal Cord Lesion Detection Compared With Standard 2-Dimensional Imaging

Tobias Kober

Objectives Fluid and white matter suppression (FLAWS) is a recently proposed magnetic resonance sequence derived from magnetization-prepared 2 rapid acquisition gradient-echo providing 2 coregistered datasets with white matter- and cerebrospinal fluid-supp ...

LIPPINCOTT WILLIAMS & WILKINS2022

Method and system for generating a three-dimensional model based on spherical photogrammetry

Pierre-André Mudry, Frédéric Kaplan, Nils Hamel, Albane Bénédicte Descombes

A computer-implemented method is proposed for creating a three-dimensional model of the environment. The method comprises the steps of planning (105) a trajectory for a moving system carrying an omnidirectional camera comprising a first image sensor facing ...

2021

Computational methods for live heart imaging with speed-constrained microscopes

Olivia Mariani

Imaging methods to capture the beating and developing heart inside embryonic animal models such as the zebrafish are a key component for the study of fundamental biological processes such as cardiac birth defects or tissue regeneration. However, live heart ...

EPFL2021

Three-dimensional imaging of integrated circuits with macro- to nanoscale zoom

Christian David, Michal Odstrcil, Gabriel Aeppli, Manuel Guizar Sicairos

The imaging of integrated circuits across different length scales is required for failure analysis, design validation and quality control. At present, such inspection is accomplished using a hierarchy of different probes, from optical microscopy on the mil ...

NATURE PUBLISHING GROUP2019

Structural and functional brain imaging using extended-focus optical coherence tomography and microscopy

Paul James Marchand

Neuroimaging techniques aim at revealing the anatomy and functional organisation of cerebral structures. Over the past decades, functional magnetic resonance imaging (fMRI) has revolutionized our understanding of human cerebral physiology through its abili ...

EPFL2018

Label-free three-dimensional imaging of Caenorhabditis elegans with visible optical coherence microscopy

Theo Lasser, Paul James Marchand, Séverine Coquoz, Johan Auwerx, Arno Pino Bouwens, Laurent Mouchiroud, Daniel Pawel Szlag, Vincenzo Sorrentino

Fast, label-free, high-resolution, three-dimensional imaging platforms are crucial for high-throughput in vivo time-lapse studies of the anatomy of Caenorhabditis elegans, one of the most commonly used model organisms in biomedical research. Despite the ne ...

Public Library of Science2017

Imaging and pattern projection through multicore fibers using the memory effect

Demetri Psaltis, Christophe Moser, Nicolino Stasio, Donald Benjaman Conkey

It is possible to focus coherent light through a multicore fiber with a resolution finer than the core-to-core spacing using digital phase conjugation. In this paper we use the memory effect and show that the displacement of the focus spot can be realized ...

Spie-Int Soc Optical Engineering2017

Two-photon fluorescence imaging through multicore fiber with digital phase conjugation

Demetri Psaltis, Christophe Moser, Nicolino Stasio, Donald Benjaman Conkey

We present near diffraction limited two photon fluorescence (TPF) imaging through a lensless, multi-core fiber (MCF) endoscope utilizing digital phase conjugation. The ultra-small size of MCFs make them desirable tools for imaging deep into the body. TPF i ...

Spie-Int Soc Optical Engineering2016

A Point-Spread-Function-Aware Filtered Backprojection Algorithm for Focal-Plane-Scanning Optical Projection Tomography

Michael Stefan Daniel Liebling

Traditional optical projection tomography requires the use of low numerical aperture objectives in order to achieve a large depth of field and approximate parallel projection geometry. However, low NA objectives suffer from poor resolution, resulting in bl ...

2016

High spectral resolution waveguide spectrometer with enhanced throughput for space and commercial applications

Mohammadreza Madi

This dissertation presents the results concerning the development of an innovative high spectral resolution waveguide spectrometer, from the concept to the prototype demonstration and the test results. The main innovative aspects of this instrument are the ...

EPFL2016

Response to "Critical Assessment of the Evidence for Striped Nanoparticles"

Francesco Stellacci, Quy Ong Khac

Stirling et al., (10.1371/journal.pone.0108482) presented an analysis on some of our publications on the formation of stripe-like domains on mixed-ligand coated gold nanoparticles. The authors shed doubts on some of our results however no valid argument is ...

Public Library of Science2015

Optical microscopy for imaging through scattering media

Xin Yang

Optical microscopy has been widely used in the life sciences and biological research for several decades. It possesses many advantages over x-ray radiography, computed tomography, ultrasound imaging and magnetic resonance imaging, in terms of being low cos ...

EPFL2014

3D high-density localization microscopy using hybrid astigmatic/biplane imaging and sparse image reconstruction

Michaël Unser, Suliana Manley, Seamus John Holden, Lina Carlini

Localization microscopy achieves nanoscale spatial resolution by iterative localization of sparsely activated molecules, which generally leads to a long acquisition time. By implementing advanced algorithms to treat overlapping point spread functions (PSFs ...

Optical Soc Amer2014

Functional and Structural Imaging with Optical Coherence Microscopy : Principles & Applications

Arno Pino Bouwens

Fluorescence microscopy techniques are well established research tools and have proven their use in a large variety of biomedical applications. Microscopic molecular contrast is achieved by imaging fluorescent dyes that bind specifically to a molecule of i ...

EPFL2013

The PANOPTIC Camera: A Plenoptic Sensor with Real-Time Omnidirectional Capability

Alexandre Schmid, Yusuf Leblebici, Pierre Vandergheynst, Luigi Bagnato, Laurent Jacques, Hossein Afshari

A new biologically-inspired vision sensor made of one hundred "eyes" is presented, which is suitable for real-time acquisition and processing of 3-D image sequences. This device, named the Panoptic camera, consists of a layered arrangement of approximately ...

Springer Verlag2013

Three-dimensional scanning microscopy through thin turbid media

Demetri Psaltis, Chia-Lung Hsieh, Ye Pu, Xin Yang, Ye Pu

We demonstrate three-dimensional imaging through a thin turbid medium using digital phase conjugation of the second harmonic signal emitted from a beacon nanoparticle. The digitally phase-conjugated focus scans the volume in the vicinity of its initial pos ...

2012

A Close Look at Proteins: Submolecular Resolution of Two- and Three-Dimensionally Folded Cytochrome c at Surfaces

Klaus Kern, Stephan Rauschenbach, Nicha Thontasen, Gordon Rinke

Imaging of individual protein molecules at the single amino acid level has so far not been possible due to the incompatibility of proteins with the vacuum environment necessary for high-resolution scanning probe microscopy. Here we demonstrate electrospray ...

American Chemical Society (ACS)2012

Digital reverse propagation in focusing Kerr media

Alexandre Goy, Demetri Psaltis

Lenses allow the formation of clear images in homogeneous linear media. Holography is an alternative imaging method, but its use is limited to cases in which it provides an advantage, such as three-dimensional imaging. In nonlinear media, lenses no longer ...

2011

Cellular Dynamics and Three-Dimensional Refractive Index Distribution Studied with Quantitative Phase Imaging

Nicolas Pavillon

We present in this PhD thesis work various applications of digital holographic microscopy (DHM), an imaging technique based on coherent illumination which enables the recovery of the full complex wavefront, i.e. the amplitude and phase of a wave field whic ...

EPFL2011