Bypassing bacterial infection in phage display by sequencing DNA released from phage particles

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The present invention provides a method for preparing a sequencing library from a ribonucleic acid (RNA) sample. ...

PremiseA novel protocol for rapid plant DNA extraction using microneedles is proposed, which supports botanic surveys, taxonomy, and systematics. This protocol can be conducted in the field with limited laboratory skills and equipment. The protocol is vali ...

Author summaryIn recent years, the application of deep learning represented a breakthrough in the mass spectrometry (MS) field by improving the assignment of the correct sequence of amino acids from observable MS spectra without prior knowledge, also known ...

The COVID-19 pandemic has highlighted the necessity to develop fast, highly sensitive and selective virus detection methods. Surface-based DNA-biosensors are interesting candidates for this purpose. Functionalization of solid substrates with DNA must be pr ...

Background and Aims:The clinical spectrum of human infection by HEV ranges from asymptomatic to severe acute hepatitis. Furthermore, HEV can cause diverse neurological manifestations, especially Parsonage-Turner syndrome. Here, we used a large-scale human ...

Acinetobacter baumannii is a dangerous nosocomial pathogen, especially due to its ability to rapidly acquire new genetic traits, including antibiotic resistance genes (ARG). In A. baumannii, natural competence for transformation, one of the primary modes o ...

Single-cell sequencing (sc-seq) provides a species agnostic tool to study cellular processes. However, these technologies are expensive and require sufficient cell quantities and biological replicates to avoid artifactual results. An option to address thes ...

The present invention relates inhibitors of acyl protein thioesterases and method of preparation thereof. It also relates to the use of inhibitors of acyl protein thioesterases in the treatment and/or prevention of a microbial infection such as viral or ba ...

Background. Respiratory syncytial virus (RSV) is associated with acute respiratory infection. We sought to identify RSV variants associated with prolonged infection. ...

Epstein–Barr virus (EBV) is one of the most common viruses latently infecting humans. Little is known about the impact of human genetic variation on the large inter-individual differences observed in response to EBV infection. To search for a potential imp ...

Bypassing bacterial infection in phage display by sequencing DNA released from phage particles

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Construction of sequencing libraries from a ribonucleic acid (rna) using tailing and ligation of cdna (tlc)

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring

Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics

Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry

Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E

DNA modifications impact natural transformation of Acinetobacter baumannii

Evaluation of genetic demultiplexing of single-cell sequencing data from model species

Inhibitors of acyl protein thioesterases against microbial infections

Viral Genetic Determinants of Prolonged Respiratory Syncytial Virus Infection Among Infants in a Healthy Term Birth Cohort

The influence of human genetic variation on Epstein–Barr virus sequence diversity