NeuroCHI: Are We Prepared for the Integration of the Brain with Computing?

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During fear learning, associations between a sensory cue (conditioned stimulus, CS) and an aversive stimulus (unconditioned stimulus, US) are formed in specific brain circuits. The lateral amygdala (LA) is involved in CS-US integration; however, US pathway ...

Long-range axons are fundamental to brain connectivity and functional organization, enabling communication between different brain regions. Recent advances in experimental techniques have yielded a substantial number of whole-brain axonal reconstructions. ...

BackgroundThe imbalance of glutamate (Glu) and gamma-aminobutyric acid (GABA) neurotransmitter system plays a crucial role in the pathogenesis of Alzheimer's disease (AD). Riluzole is a Glu modulator originally approved for amyotrophic lateral sclerosis th ...

Discovering principles underlying the control of animal behavior requires a tight dialogue between experiments and neuromechanical models. Such models have primarily been used to investigate motor control with less emphasis on how the brain and motor syste ...

Aging populations face significant cognitive challenges, particularly in working memory (WM). Transcranial alternating current stimulation (tACS) offer promising avenues for cognitive enhancement, especially when inspired by brain physiology. This study (N ...

BackgroundImplantable vagus nerve stimulation is a promising approach for restoring autonomic cardiovascular functions after heart transplantation. For successful treatment a system should have multiple electrodes to deliver precise stimulation and complex ...

Background: Clinical and translational research has identified deficits in the dopaminergic neurotransmission in the striatum in Alzheimer's disease (AD) and this could be related to the pathophysiology of psychiatric symptoms appearing even at early stage ...

Neurological impairments and diseases can be diagnosed or treated using electrocorticography (ECoG) arrays. In drug-resistant epilepsy, these help delineate the epileptic region to resect. In long-term applications such as brain-computer interfaces, these ...

Astrocytes connect the vasculature to neurons mediating the supply of nutrients and biochemicals. They are involved in a growing number of physiological and pathophysiological processes that result from biophysical, physiological, and molecular interaction ...

Gyrification of the cerebral cortex is a developmentally important process, but the mechanisms that drive cortical folding are not fully known. Theories propose that changes within the cortical plate (CP) cause gyrification, yet differences between the CP ...

Error-related EEG potentials (ErrP) can be used for brain-machine interfacing (BMI). Decoding of these signals, indicating subject's perception of erroneous system decisions or actions can be used to correct these actions or to improve the overall interfac ...

Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged alon ...

Intensive research over the past few years has provided evidence, that stress is a potent modulator of brain function and cognition. In particular cognitive and emotional processes have been shown to be susceptible to modulation by stress. Whereas acute st ...

NeuroCHI: Are We Prepared for the Integration of the Brain with Computing?

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A posterior insula to lateral amygdala pathway transmits US-offset information with a limited role in fear learning

Computational Generation of Long-range Axonal Morphologies

CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer's disease mice

NeuroMechFly v2: simulating embodied sensorimotor control in adult Drosophila

Physiology-inspired bifocal fronto-parietal tACS for working memory enhancement

A Multi-channel Stimulator with an Active Electrode Array Implant for Vagal-cardiac Neuromodulation Studies

Impairment of hippocampal astrocyte-mediated striatal dopamine release and locomotion in Alzheimer's disease

Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs

Digital Reconstruction of the Neuro-Glia-Vascular Architecture

Genetic and microstructural differences in the cortical plate of gyri and sulci during gyrification in fetal sheep

Decoding Fast-Paced Error-Related Potentials in Monitoring Protocols

Brain–machine interface: closer to therapeutic reality?

Implantable probe for stimulating neurological target e.g. neurons and subthalamic nucleus, has several microelectrode elements arranged at distal end of elongated probe shaft, and electrical contact arranged proximally along shaft

Effects of the cumulative exposure to Lypopolysaccharide and Hyperoxia on the developing rat brain assessed by high-field diffusion tensor imaging

Stress-induced cognitive and psychopathological alterations : functional involvement of the neural cell adhesion molecule (NCAM)