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Quantitative Estimation of Biological Cell Surface Receptors by Segmenting Conventional Fluorescence Microscopy Images

Related publications (32)

Burst Vision Using Single-Photon Cameras

Single-photon avalanche diodes (SPADs) are novel image sensors that record the arrival of individual photons at extremely high temporal resolution. In the past, they were only available as single pixels or small-format arrays, for various active imaging ap ...

IEEE COMPUTER SOC2023

Computational Imaging SPAD Cameras

Andrei Ardelean

Vision systems built around conventional image sensors have to read, encode and transmit large quantities of pixel information, a majority of which is redundant. As a result, new computational imaging sensor architectures were developed to preprocess the r ...

EPFL2023

Label-free plasmonic microarray for multiplexed analysis of cells and tumor organoids

Yen-Cheng Liu

Investigating the dynamic activities of protein expression and signaling in living organisms is a crucial focus of intense research aimed at elucidating the processes that underlie disease progression and improving treatments and drug development. Resolvin ...

EPFL2023

Wideband integrated bioaerosol sensor (WIBS) excited, fluorescent, and hyper-fluorescent particle number concentrations and normalized size distributions (dN/dlogDp) measured in the Swiss container during MOSAiC 2019/2020

Julia Schmale, Ivo Fabio Beck, Margarida Teles Nogueira Rolo, Alireza Moallemi

These datasets contain the total particle number concentrations and normalized size distributions (dN/dlogDp) of excited, fluorescent, and hyper-fluorescent particles of sizes 0.5 to 20 μm (optical diameter). The normalized size distribution datasets are s ...

Zenodo2023

Recycling of Polymerase Chain Reaction (PCR) Kits

Francesco Stellacci, Yong Zhu, Weina Liu

Polymerase chain reaction (PCR) kits have been used as common diagnosing tools during the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, with daily worldwide usage in the millions. It is well known that at the beginn ...

AMER CHEMICAL SOC2023

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Florian Maria Wurm, Guillaume Raussin

Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood mononuclear ...

MDPI2023

Evaluation of HPK n plus -p planar pixel sensors for the CMS Phase-2 upgrade

Rakesh Chawla, Albert Perez, François Robert, Andrea Rizzi, Martin Fuchs, Stefano Michelis, Alexis Kalogeropoulos, Varun Sharma, Davide Ceresa, Ashish Sharma, David Vannerom, David Parker, Alessandro Caratelli, Thomas Muller, Yong Yang, Kai Yi, Andromachi Tsirou, Georgios Anagnostou, Konstantin Androsov, Ajay Kumar, Werner Lustermann, Xin Chen, Jing Li

To cope with the challenging environment of the planned high luminosity upgrade of the Large Hadron Collider (HL-LHC), scheduled to start operation in 2029, CMS will replace its entire tracking system. The requirements for the tracker are largely determine ...

Elsevier2023

Efficient and sensitive profiling of RNA–protein interactions using TLC-CLIP

Didier Trono, Julien Léonard Duc, Christina Ernst

RNA-binding proteins are instrumental for post-transcriptional gene regulation, controlling all aspects throughout the lifecycle of RNA molecules. However, transcriptome-wide methods to profile RNA-protein interactions in vivo remain technically challengin ...

2023

Revisiting Evaluation Metrics for Semantic Segmentation: Optimization and Evaluation of Fine-grained Intersection over Union

Devis Tuia, Zifu Wang

Semantic segmentation datasets often exhibit two types of imbalance: \textit{class imbalance}, where some classes appear more frequently than others and \textit{size imbalance}, where some objects occupy more pixels than others. This causes traditional eva ...

2023

Detecting Anomalies and Obstacles in Road Scenes

Krzysztof Maciej Lis

We address the problem of segmenting anomalies and unusual obstacles in road scenes for the purpose of self-driving safety. The objects in question are not present in the common training sets as it is not feasible to collect and annotate examples for every ...

EPFL2023

A general strategy to develop fluorogenic polymethine dyes for bioimaging

Pablo Rivera Fuentes, Annabell Martin

Fluorescence imaging is an invaluable tool to study biological processes and further progress depends on the development of advanced fluorogenic probes that reach intracellular targets and label them with high specificity. Excellent fluorogenic rhodamine d ...

Nature Portfolio2023

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase(+) cells and telomeric recombination in ALT(+) cells

Joachim Lingner, Rita Valador Fernandes

Telomeres are the nucleoprotein structures at the ends of linear chromosomes. Telomeres are transcribed into long non-coding Telomeric Repeat-Containing RNA (TERRA), whose functions rely on its ability to associate with telomeric chromatin. The conserved T ...

OXFORD UNIV PRESS2023