Long-distance runningLong-distance running, or endurance running, is a form of continuous running over distances of at least . Physiologically, it is largely aerobic in nature and requires stamina as well as mental strength. Within endurance running comes two different types of respiration. The more prominent side that runners experience more frequently is aerobic respiration. This occurs when oxygen is present, and the body can utilize oxygen to help generate energy and muscle activity.
Neural crestNeural crest cells are a temporary group of cells that arise from the embryonic ectoderm germ layer, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, peripheral and enteric neurons and glia. After gastrulation, neural crest cells are specified at the border of the neural plate and the non-neural ectoderm. During neurulation, the borders of the neural plate, also known as the neural folds, converge at the dorsal midline to form the neural tube.