Publication

Cross Validation of Experts Versus Registration Methods for Target Localization in Deep Brain Stimulation

Jean-Philippe Thiran, Meritxell Bach Cuadra, Olivier Cuisenaire
2005
Conference Papers

Abstract

In the last five years, Deep Brain Stimulation (DBS) has become the most popular and effective surgical technique for the treatment of Parkinson s disease (PD). The Subthalamic Nucleus (STN) is the usual target involved when applying DBS. Unfortunately, the STN is in general not visible in common medical imaging modalities. Therefore, atlas-based segmentation is commonly considered to locate it in the images. In this paper, we propose a scheme that allows both, to perform a comparison between different registration algorithms and to evaluate their ability to locate the STN automatically. Using this scheme we can evaluate the expert variability against the error of the algorithms and we demonstrate that automatic STN location is possible and as accurate as the methods currently used.

Official source

https://infoscience.epfl.ch/entities/publication/e31f6d42-9426-4926-ad10-ffb3961c7849

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Jean-Philippe Thiran, Meritxell Bach Cuadra, Olivier Cuisenaire
2005
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/e31f6d42-9426-4926-ad10-ffb3961c7849

About this result

Related concepts (28)

Deep brain stimulation

Deep brain stimulation (DBS) is a neurosurgical procedure involving the placement of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to specific targets in the brain (the brain nucleus) for the treatment of movement disorders, including Parkinson's disease, essential tremor, dystonia, and other conditions such as obsessive-compulsive disorder (OCD) and epilepsy. While its underlying principles and mechanisms are not fully understood, DBS directly changes brain activity in a controlled manner.

Medical imaging

Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities.

Image registration

Image registration is the process of transforming different sets of data into one coordinate system. Data may be multiple photographs, data from different sensors, times, depths, or viewpoints. It is used in computer vision, medical imaging, military automatic target recognition, and compiling and analyzing images and data from satellites. Registration is necessary in order to be able to compare or integrate the data obtained from these different measurements.

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Cross Validation of Experts Versus Registration Methods for Target Localization in Deep Brain Stimulation

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