Publication

Fourier Domain Optical Coherence Microscopy with Extended Depth of Field

Theo Lasser, Marcel Leutenegger
2008
Posters

Abstract

Fourier Domain Optical Coherence Tomography (FDOCT) is a high speed biomedical imaging modality which extracts the sample structure in depth. The axial resolution is given by the coherence length of the employed light source. The lateral resolution on the other hand is determined by the numerical aperture (NA) of the objective. The parallel detection of the depth information has the drawback of loosing transverse resolution along the optical axis, limiting the depth of field (DOF) and the use of FDOCT in the field of microscopy. The principle idea to overcome this problem is to illuminate the sample with a cylindrically symmetric interference pattern. Such Bessel beam illumination creates a laterally highly confined needle extending several 100μm along the optical axis in depth.

Official source

https://infoscience.epfl.ch/entities/publication/e24e4927-b1e1-48c1-9c73-8fe32db5d54e

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Theo Lasser, Marcel Leutenegger
2008
Posters

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/e24e4927-b1e1-48c1-9c73-8fe32db5d54e

About this result

Related concepts (32)

Optical coherence tomography

Optical coherence tomography (OCT) is an imaging technique that uses low-coherence light to capture micrometer-resolution, two- and three-dimensional images from within optical scattering media (e.g., biological tissue). It is used for medical imaging and industrial nondestructive testing (NDT). Optical coherence tomography is based on low-coherence interferometry, typically employing near-infrared light. The use of relatively long wavelength light allows it to penetrate into the scattering medium.

Super-resolution microscopy

Super-resolution microscopy is a series of techniques in optical microscopy that allow such images to have resolutions higher than those imposed by the diffraction limit, which is due to the diffraction of light. Super-resolution imaging techniques rely on the near-field (photon-tunneling microscopy as well as those that use the Pendry Superlens and near field scanning optical microscopy) or on the far-field.

Fourier optics

Fourier optics is the study of classical optics using Fourier transforms (FTs), in which the waveform being considered is regarded as made up of a combination, or superposition, of plane waves. It has some parallels to the Huygens–Fresnel principle, in which the wavefront is regarded as being made up of a combination of spherical wavefronts (also called phasefronts) whose sum is the wavefront being studied. A key difference is that Fourier optics considers the plane waves to be natural modes of the propagation medium, as opposed to Huygens–Fresnel, where the spherical waves originate in the physical medium.

Related publications (18)

Fourier Domain Optical Coherence Microscopy with Extended Depth of Field

Chat with Graph Search

Revisiting PSF models: Unifying framework and high‐performance implementation

SiR‐XActin: A Fluorescent Probe for Imaging Actin Dynamics in Live Cells

Design and Fabrication of Piezoelectric Trampoline Resonators for Nanomechanical Photothermal Sensing