Publications related to Viral peptide conjugates for metal-warhead delivery to chromatin

Related publications (6)

Structure-Activity Relationship Studies of Glycosaminoglycan Mimetic Macrocycles Against Herpes

Cynthia Paloma Aigroz, Hien Tran Thi, Deepika Sardana, Anita Zucchi, Francesco Stellacci, Paulo Henrique Jacob Silva, Melis Özkan, Sujeet Pawar

The herpes simplex virus (HSV) is associated with serious conditions, such as encephalitis and blindness, and its infection is closely linked to significant vascular complications and coagulation issues, particularly in individuals with compromised immune ...

AMER CHEMICAL SOC2025

The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy flux

Maurizio Molinari

Organellophagy receptors control the generation and delivery of portions of their homing organelle to acidic degradative compartments to recycle nutrients, remove toxic or aged macromolecules and remodel the organelle upon physiologic or pathologic cues. H ...

2025

Modulating the DNA/Lipid Interface through Multivalent Hydrophobicity

Yann Zosso, Sarina Nicole Kopf, Maartje Martina Cornelia Bastings, Vincenzo Caroprese, Diana Kornelia Morzy, Siu Ho Wong

Lipids and nucleic acids are two of the most abundant components of our cells, and both molecules are widely used as engineering materials for nanoparticles. Here, we present a systematic study of how hydrophobic modifications can be employed to modulate t ...

American Chemical Society (ACS)2024

A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation

Freddy Radtke, Bart Deplancke, Ute Koch, Vincent Roland Julien Gardeux, Riccardo Dainese, Daniel Alpern, Jörn Pezoldt, Julie Marie Russeil, Maria Litovchenko, Gerard Llimos Aubach, Judith Franziska Kribelbauer

Non-coding variants coordinate transcription factor (TF) binding and chromatin mark enrichment changes over regions spanning >100 kb. These molecularly coordinated regions are named "variable chromatin modules" (VCMs), providing a conceptual framework of h ...

Nature Portfolio2022

Proteome-wide analysis of protein lipidation using chemical probes: in-gel fluorescence visualization, identification and quantification of N-myristoylation, N- and S-acylation, O-cholesterylation, S-farnesylation and S-geranylgeranylation

Paulina Teresa Ciepla, Nattawadee Panyain

Protein lipidation is challenging to analyze on the proteome level. This protocol describes metabolic incorporation of lipid probes and their capture via click chemistry, allowing in-gel fluorescence visualization or mass spectrometry analysis. ...

NATURE PORTFOLIO2021

Bead-based single protein micro-array realized through electrostatic self-assembly of carboxylated beads

Martinus Adela Maria Gijs, Abdeljalil Sayah, Venkataragavalu Sivagnanam

We report here a simple method, based on electrostatic self-assembly, for realizing bead-based single protein micro-arrays. We generate positively charged surface micro-patterns on a glass substrate and use them as template for adsorbing negatively-charged ...

2008