Publication

Access to Macrocycles with an endo Aryl ether and an endo Aryl-Aryl Bond, Development and Application

Jieping Zhu, Qian Wang
2011
Journal Articles

Abstract

Macrocyclization methodologies allowing access to macrocycles having an endo ary ether and an endo ary-aryl bond, especially those based on an intramolecular SNAr reaction and the Suzuki-Miyaura reaction, were summarized. Total synthesis of complestatin, a bis-macrocyclic natural product, featuring these two technologies was presented.

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