Publication

Chemotactic Behaviour of <i>giardia Lamblia</i> and <i>trichomonas Vaginalis</i> Towards Nutrient Sources

2025

Abstract

Chemotaxis is the phenomenon of sensing external concentration gradients by cells and the cellular movement towards or away from the cells. While there have been intensive studies on prokaryotes, little research has been conducted on the chemotaxis in flagellated eukaryotes, such as Giardia lamblia (G. lamblia) and Trichomonas vaginalis (T. vaginalis). The current study uses a 2-chamber assay to discuss the motility of G. lamblia and T. vaginalis towards simple sugars. The cells were observed moving towards the sugars in a concentration and time-dependent manner. Furthermore, the cell movements were independent of change in osmolarity. Experiments compared the motility of the parasites grown in TYI-S-33 medium and TYI-S-33 medium without glucose (starvation media). It was noted that the starved cells showed a better chemotactic response towards the carbohydrates than the non-starved cells.

Official source

https://infoscience.epfl.ch/entities/publication/dad42559-f0a6-4589-9fa4-1c9172e3990b

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2025

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/dad42559-f0a6-4589-9fa4-1c9172e3990b

About this result

Related concepts (32)

Chemotaxis

Chemotaxis (from chemo- + taxis) is the movement of an organism or entity in response to a chemical stimulus. Somatic cells, bacteria, and other single-cell or multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food (e.g., glucose) by swimming toward the highest concentration of food molecules, or to flee from poisons (e.g., phenol). In multicellular organisms, chemotaxis is critical to early development (e.g.

Sugar

Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double sugars, are molecules made of two bonded monosaccharides; common examples are sucrose (glucose + fructose), lactose (glucose + galactose), and maltose (two molecules of glucose). White sugar is a refined form of sucrose. In the body, compound sugars are hydrolysed into simple sugars.

Giardia duodenalis

Giardia duodenalis, also known as Giardia intestinalis and Giardia lamblia, is a flagellated parasitic microorganism of the genus Giardia that colonizes the small intestine, causing a diarrheal condition known as giardiasis. The parasite attaches to the epithelium by a ventral adhesive disc or sucker, and reproduces via binary fission. Giardiasis does not spread via the bloodstream, nor does it spread to other parts of the gastrointestinal tract, but remains confined to the lumen of the small intestine.

Related publications (12)

Chemotactic Behaviour of <i>giardia Lamblia</i> and <i>trichomonas Vaginalis</i> Towards Nutrient Sources

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