A Synthetic Factor XIIa Inhibitor Blocks Selectively Intrinsic Coagulation Initiation

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Background Physical frailty and loss of mobility in elderly individuals lead to reduced independence, quality of life, and increased mortality. Vitamin B12 deficiency has been linked to several age-related chronic diseases, including in the musculo-skeleta ...

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Factor XII (FXII) is a plasma protease that has emerged in recent years as a potential target to treat or prevent pathological thrombosis, to inhibit contact activation in extracorporeal circulation, and to treat the swelling disorder hereditary angioedema ...

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A Synthetic Factor XIIa Inhibitor Blocks Selectively Intrinsic Coagulation Initiation

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