Publication

Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?

Maurizio Molinari
2017
Journal Articles

Abstract

Amplification of the candidate oncogene TLOC1/SEC62 in tumors correlates with reduced patient survival. The recently reported role of SEC62 as an autophagy receptor that controls endoplasmic reticulum (ER) size and function might open new scenarios for understanding the phenotypes and treat SEC62high tumors, which are characterized by high ER stress tolerance.

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Maurizio Molinari
2017
Journal Articles

Abstract

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Related concepts (8)

Gender role

A gender role, also known as a sex role, is a social role encompassing a range of behaviors and attitudes that are generally considered acceptable, appropriate, or desirable for a person based on that person's sex. Gender roles are usually centered on conceptions of masculinity and femininity, although there are exceptions and variations. The specifics regarding these gendered expectations may vary among cultures, while other characteristics may be common throughout a range of cultures.

Role-playing

Role-playing or roleplaying is the changing of one's behaviour to assume a role, either unconsciously to fill a social role, or consciously to act out an adopted role. While the Oxford English Dictionary offers a definition of role-playing as "the changing of one's behaviour to fulfill a social role", in the field of psychology, the term is used more loosely in four senses: To refer to the playing of roles generally such as in a theatre, or educational setting; To refer to taking a role of a character or person and acting it out with a partner taking someone else's role, often involving different genres of practice; To refer to a wide range of games including role-playing video game (RPG), play-by-mail games and more; To refer specifically to role-playing games.

Role

A role (also rôle or social role) is a set of connected behaviors, rights, obligations, beliefs, and norms as conceptualized by people in a social situation. It is an expected or free or continuously changing behavior and may have a given individual social status or social position. It is vital to both functionalist and interactionist understandings of society. Social role theory posits the following about social behavior: The division of labour in society takes the form of the interaction among heterogeneous specialized positions, we call roles.

Related publications (3)

Role of SEC62 in ER maintenance: A link with ER stress tolerance in SEC62-overexpressing tumors?

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