Publications related to Exchangeable HaloTag Ligands for Super-Resolution Fluorescence Microscopy

Related publications (9)

Intelligent and Self-Driving Microscopy of Protein Aggregation in Neurodegenerative Diseases

Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and Huntington's, afflict tens of millions of patients worldwide. They are characterized by protein aggregation and progressive neuronal loss, leading to cognitive and motor impairments, and ult ...

EPFL2025

Optical tweeze-sectioning microscopy for 3D imaging and manipulation of suspended cells

Xiaohao Xu, Olivier Martin, Siarhei Zavatski

Optical manipulation and detection of biological particulates are crucial procedures in biophotonics. Optical sectioning (OS) opens the avenue to three-dimensional (3D) microscopy, but nonoptical approaches, including sample adhesion and mechanical scannin ...

American Association for the Advancement of Science (AAAS)2025

Spatial and stoichiometric in situ analysis of biomolecular oligomerization at single-protein resolution

Maartje Martina Cornelia Bastings

Latest advances in super-resolution microscopy allow the study of subcellular features at the level of single proteins, which could lead to discoveries in fundamental biological processes, specifically in cell signaling mediated by membrane receptors. Desp ...

Springer Science and Business Media LLC2025

Membrane Potential Fluctuations and Water Asymmetry on Plasma Cell and Model Lipid Membranes: Origins, Implications and Properties

Nelson Alonso Correa Rojas, Lena Dalifoski, Sylvie Roke, Arianna Marchioro, Orly Bagunu Tarun, David Roesel, Maksim Eremchev, Seonwoo Lee, Mischa Samuel Flór, Bryan Zhi Li, Iwona Swiderska

Membrane potential fluctuations have previously been detected using second harmonic (SH) water imaging on neuronal cells and model lipid bilayer membranes. We report that such fluctuations are also visible when membrane potential-sensitive fluorophores are ...

ROYAL SOC CHEMISTRY2025

Dissecting the mechanisms of centriole stability in Caenorhabditis elegans: Focus on SAS-1

Keshav Jha

Centrioles are evolutionarily conserved microtubule-based organelles essential for cell division, ciliogenesis, and cell polarity. While centrioles are critical for many cellular processes, their selective elimination is crucial during specific development ...

EPFL2025

Peptide‐Carbazolyl Cyanobenzene Conjugates: Enabling Biomolecule Functionalization via Photoredox and Energy Transfer Catalysis

Jérôme Waser, Beat Fierz, Anne-Sophie Chauvin, Xingyu Liu, Wei Cai

Since their discovery in 2012, carbazolyl (iso)phthalonitrile derivatives (Cz(I)PN) have found significant applications as photocatalysts in organic chemistry. Herein, we introduce two efficient methods for incorporating carbazolyl cyanobenzenes into vario ...

Wiley2025

Optical imaging of molecules and their dynamics from surfaces to nanoscale confinement

Nathan Cyprien Arsène Ronceray

Molecular behavior can change dramatically at interfaces, and these changes become even more pronounced when molecules are confined within nanoscale dimensions. In living organisms, nanoscale channels play a crucial role in selectively transporting molecul ...

EPFL2024

Focus image scanning microscopy for sharp and gentle super-resolved microscopy

Giorgio Tortarolo

To date, the feasibility of super-resolution microscopy for imaging live and thick samples is still limited. Stimulated emission depletion (STED) microscopy requires high-intensity illumination to achieve sub-diffraction resolution, potentially introducing ...

Nature Portfolio2022

Molecular Stabilization of Sub-Nanometer Cu Clusters for Selective CO2 Electromethanation

Jun Li

Electrochemical CO2 methanation powered by renewable electricity provides a promising approach to utilizing CO2 in the form of a high-energy-density, clean fuel. Cu nanoclusters have been predicted by theoretical calculations to improve methane selectivity ...

WILEY-V C H VERLAG GMBH2022