Publication

Binding of organoruthenium anticancer drugs to DNA

Ursula Röthlisberger, Ivano Tavernelli, Christian Gossens
2005
Conference Papers

Abstract

Organoruthenium compds. have emerged as promising novel anticancer agents but very little is known about their mol. mechanism of action. Here, we present classical and mixed QM/MM first-principles MD simulations of two ruthenium(II) compds. and their binding to DNA. [on SciFinder (R)]

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Binding of organoruthenium anticancer drugs to DNA

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