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High-throughput sequencing (HTS) data are commonly stored as raw sequencing reads in FASTQ format or as reads mapped to a reference, in SAM format, both with large memory footprints. Worldwide growth of HTS data has prompted the development of compression methods that aim to significantly reduce HTS data size. Here we report on a benchmarking study of available compression methods on a comprehensive set of HTS data using an automated framework.
Bart Deplancke, Riccardo Dainese, Daniel Alpern, Mustafa Demir, Dariia Gudkova
Tamar Kohn, Xavier Fernandez Cassi
Touradj Ebrahimi, Michela Testolina, Davi Nachtigall Lazzarotto