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A 3D Microscaffold Cochlear Electrode Array for Steroid Elution

Related publications (32)

Sensitivity to temporal parameters of intraneural tactile sensory feedback

Edoardo D'Anna, Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Background Recent studies have shown that neural stimulation can be used to provide artificial sensory feedback to amputees eliciting sensations referred on the amputated hand. The temporal properties of the neural stimulation modulate aspects of evoked se ...

BioMed Central2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Nicolas Vachicouras

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

LIPPINCOTT WILLIAMS & WILKINS2020

Longitudinal neural and vascular structural dynamics produced by chronic microelectrode implantation

Andrea Lozzi

Implanted microelectrode arrays sense local neuronal activity, signals which are used as control commands for brain computer interface (BCI) technology. Patients with tetraplegia have used BCI technology to achieve an extraordinary degree of interaction wi ...

2020

Integration of hybrid material systems in conformable neural interfaces

Florian Dylan Fallegger

Neural interfaces are devices that are implanted into the body and interface electrically with the central (CNS) or peripheral nervous system. They are inserted surgically for short periods of time or chronically to diagnose or treat several neural disease ...

EPFL2020

Closed-Loop Neural Interfaces with Embedded Machine Learning

Mahsa Shoaran, Uisub Shin, Bingzhao Zhu

Neural interfaces capable of multi-site electrical recording, on-site signal classification, and closed-loop therapy are critical for the diagnosis and treatment of neurological disorders. However, deploying machine learning algorithms on low-power neural ...

IEEE2020

Tutorial: a computational framework for the design and optimization of peripheral neural interfaces

Silvestro Micera, Giacomo Valle, Simone Romeni

Peripheral neural interfaces have been successfully used in the recent past to restore sensory-motor functions in disabled subjects and for the neuromodulation of the autonomic nervous system. The optimization of these neural interfaces is crucial for ethi ...

NATURE RESEARCH2020

Soft Printable Electrode Coating for Neural Interfaces

Florian Dylan Fallegger, Elvira Pirondini, Stéphanie Lacour, Arnaud Bichat, Grégoire Courtine, Quentin Barraud, Michael Shur

The mechanical mismatch between implantable interfaces and neural tissues may be reduced by employing soft polymeric materials. Here, we report on a simple strategy to prepare and pattern a soft electrode coating of neural interfacing devices based on a sc ...

2020

A Review of Microelectronic Systems and Circuit Techniques for Electrical Neural Recording Aimed at Closed-Loop Epilepsy Control

Alexandre Schmid, Reza Ranjandish

Closed-loop implantable electronics offer a new trend in therapeutic systems aimed at controlling some neurological diseases such as epilepsy. Seizures are detected and electrical stimulation applied to the brain or groups of nerves. To this aim, the signa ...

2020

Hand Control With Invasive Feedback Is Not Impaired by Increased Cognitive Load

Edoardo D'Anna, Silvestro Micera, Francesco Maria Petrini, Ivo Strauss, Giacomo Valle

Recent experiments have shown that neural stimulation can successfully restore sensory feedback in upper-limb amputees improving their ability to control the prosthesis. However, the potential advantages of invasive sensory feedback with respect to non-inv ...

2020

Directional Local Field Potentials in the Subthalamic Nucleus During Deep Brain Implantation of Parkinson's Disease Patients

André Mercanzini, Thuy Anh Khoa Nguyen

Segmented deep brain stimulation leads feature directional electrodes that allow for a finer spatial control of electrical stimulation compared to traditional ring-shaped electrodes. These segmented leads have demonstrated enlarged therapeutic windows and ...

2020

Microstructured thin-film electrode technology enables proof of concept of scalable, soft auditory brainstem implants

Nicolas Vachicouras, Florian Dylan Fallegger, Stéphanie Lacour, Christina Myra Tringides, Jennifer Mary Adrienne Alice Macron, Yohann Daniel André Thenaisie, Valentina Marie Paggi

Auditory brainstem implants (ABIs) provide sound awareness to deaf individuals who are not candidates for the cochlear implant. The ABI electrode array rests on the surface of the cochlear nucleus (CN) in the brainstem and delivers multichannel electrical ...

2019

Auditory Brainstem Implants: Recent Progress and Future Perspectives

Nicolas Vachicouras, Stéphanie Lacour

The auditory brainstem implant (ABI) was first developed nearly 40 years ago and provides auditory rehabilitation to patients who are deaf and ineligible for cochlear implant surgery due to abnormalities of the cochlea and cochlear nerve. The aims of the f ...

2019