Publications related to An Immunomodulatory Gallotanin-Rich Fraction From Caesalpinia spinosa Enhances the Therapeutic Effect of Anti-PD-L1 in Melanoma

Related publications (8)

Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains

Outbreaks of chilblains were reported during the COVID-19 pandemic. Given the essential role of type I interferon (I-IFN) in protective immunity against SARS-CoV-2 and the association of chilblains with inherited type I interferonopathies, we hypothesized ...

ROCKEFELLER UNIV PRESS2025

Mammary Intraepithelial Lymphocytes and Intestinal Inputs Shape T Cell Dynamics in Lactogenesis

Siba Smarak Panigrahi, Maurizio Fiusco, Maria Brbic

Pregnancy brings about profound changes in the mammary gland to prepare for lactation, yet immunocyte changes that accompany this rapid remodeling are incompletely understood. We comprehensively analyzed mammary T cells, revealing a marked increase in CD4+ ...

NATURE PORTFOLIO2025

Neonatal leucocyte cell population data: reference intervals and relevance for detecting sepsis and necrotizing enterocolitis

Raphaël Matusiak

Background Timely diagnosis of neonatal sepsis is crucial but remains challenging. Cell Population Data (CPD) provide high-resolution phenotyping of leukocytes, offering potential for sepsis detection. We aimed to establish neonatal CPD reference intervals ...

Springer Science and Business Media LLC2025

Rapid Universal Detection of High‐Risk and Low‐Abundance Microbial Contaminations in CAR‐T Cell Therapy (Small Methods 8/2025)

Alexander Jeremias Odermatt

Wiley2025

tRNA-derived fragments in T lymphocyte-beta cell crosstalk and in type 1 diabetes pathogenesis in NOD mice

Nicolas Jean Philippe Guex, Christian Iseli

Aims/hypothesistRNAs play a central role in protein synthesis. Besides this canonical function, they were recently found to generate non-coding RNA fragments (tRFs) regulating different cellular activities. The aim of this study was to assess the involveme ...

SPRINGER2024

Boosting CAR T-cell therapy through G-protein signal rewiring

Liyan Yang Smeding

Chimeric antigen receptor (CAR) T-cell therapy continues to struggle in reaching its full potential in solid tumors, largely due to the tumor microenvironment (TME) where various small molecules induce immunosuppressive signaling in CAR T-cells. Two key mo ...

EPFL2024

Fine-tuning the cytotoxicity of ruthenium(ii) arene compounds to enhance selectivity against breast cancers

Paul Joseph Dyson

Ruthenium-based complexes have been suggested as promising anticancer drugs exhibiting reduced general toxicity compared to platinum-based drugs. In particular, Ru(& eta;(6)-arene)(PTA)Cl-2 (PTA = 1,3,5-triaza-7-phosphaadamantane), or RAPTA, complexes have ...

ROYAL SOC CHEMISTRY2023

Altered immune responses in mice without initial dermal lymphatics

Melody Swartz, Sachiko Hirosue

Karger2009