Publication

A Cross Validation Study of STN targeting on MRI: from Stereotactic Procedures and Automatic Registration Algorithms to direct identification

Jean-Philippe Thiran
2006
Conference Papers

Abstract

Subthalamic nucleus (STN) Deep brain stimulation (DBS) has demonstrated its efficacy in the treatment of Parkinson´s disease. Accurate targeting of the STN is a crucial step for the success of DBS surgery. MRI has shown to be reliable and allows direct targeting. Unfortunately, STN is not always clearly identifiable on standard T2-weighted images. In these situations, manual targeting procedures represent only an estimation of the real STN position. Recently, registration algorithms have been developed to automatically estimate the position of brain structures from segmented electronic atlases. However, their precision remains to be studied. We propose to evaluate the performance of different targeting methods (manual and automatic) compared to expert accuracy.

Official source

https://infoscience.epfl.ch/entities/publication/d0dcb64d-559f-4d7b-aa70-4e41cf1dc1dc

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Jean-Philippe Thiran
2006
Conference Papers

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/d0dcb64d-559f-4d7b-aa70-4e41cf1dc1dc

About this result

Related concepts (32)

Deep brain stimulation

Deep brain stimulation (DBS) is a neurosurgical procedure involving the placement of a medical device called a neurostimulator, which sends electrical impulses, through implanted electrodes, to specific targets in the brain (the brain nucleus) for the treatment of movement disorders, including Parkinson's disease, essential tremor, dystonia, and other conditions such as obsessive-compulsive disorder (OCD) and epilepsy. While its underlying principles and mechanisms are not fully understood, DBS directly changes brain activity in a controlled manner.

Target market

A target market, also known as serviceable obtainable market (SOM), is a group of customers within a business's serviceable available market at which a business aims its marketing efforts and resources. A target market is a subset of the total market for a product or service. The target market typically consists of consumers who exhibit similar characteristics (such as age, location, income or lifestyle) and are considered most likely to buy a business's market offerings or are likely to be the most profitable segments for the business to service by OCHOM Once the target market(s) have been identified, the business will normally tailor the marketing mix (4 Ps) with the needs and expectations of the target in mind.

Brain

A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons.

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A Cross Validation Study of STN targeting on MRI: from Stereotactic Procedures and Automatic Registration Algorithms to direct identification

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