Publication

Detection and investigation of biological molecules by fourier transform infra-red spectroscopy

Horst Arthur Vogel
2000
Patents

Abstract

Method and apparatus to study biological molecules or biological components at or in self-assembled monolayers (SAMs) on metal surfaces (2) such as gold in aqueous environments (6) using attenuated total internal reflection Fourier transform infra-red (ATR-FTIR) spectroscopy are described. Said method may be used for e.g. the screening for effective substances suitable as agonists or antagonists or - if performed time resolved - for studying kinetics of interactions of e.g. biological molecules adsorption and desorption processes or for the development of materials and surfaces for biological or medical applications.

Official source

https://infoscience.epfl.ch/entities/publication/cfe8f249-baf6-4567-bb1a-d40871c4fde7

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Horst Arthur Vogel
2000
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/cfe8f249-baf6-4567-bb1a-d40871c4fde7

About this result

Related concepts (28)

Infrared spectroscopy

Infrared spectroscopy (IR spectroscopy or vibrational spectroscopy) is the measurement of the interaction of infrared radiation with matter by absorption, emission, or reflection. It is used to study and identify chemical substances or functional groups in solid, liquid, or gaseous forms. It can be used to characterize new materials or identify and verify known and unknown samples. The method or technique of infrared spectroscopy is conducted with an instrument called an infrared spectrometer (or spectrophotometer) which produces an infrared spectrum.

Fourier-transform spectroscopy

Fourier-transform spectroscopy is a measurement technique whereby spectra are collected based on measurements of the coherence of a radiative source, using time-domain or space-domain measurements of the radiation, electromagnetic or not. It can be applied to a variety of types of spectroscopy including optical spectroscopy, infrared spectroscopy (FTIR, FT-NIRS), nuclear magnetic resonance (NMR) and magnetic resonance spectroscopic imaging (MRSI), mass spectrometry and electron spin resonance spectroscopy.

Spectroscopy

Spectroscopy is the field of study that measures and interprets the electromagnetic spectra that result from the interaction between electromagnetic radiation and matter as a function of the wavelength or frequency of the radiation. Matter waves and acoustic waves can also be considered forms of radiative energy, and recently gravitational waves have been associated with a spectral signature in the context of the Laser Interferometer Gravitational-Wave Observatory (LIGO).

Related publications (32)

Detection and investigation of biological molecules by fourier transform infra-red spectroscopy

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