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Asymmetrical flow field-flow fractionation coupled to multi-angle light scattering detector: optimization of crossflow rate, carrier characteristics and injected mass in alginate separation

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Related publications (31)

Constraining the response factors of an extractive electrospray ionization mass spectrometer for near-molecular aerosol speciation

Yandong Tong, Julia Schmale, Imad El Haddad

Online characterization of aerosol composition at the near-molecular level is key to understanding chemical reaction mechanisms, kinetics, and sources under various atmospheric conditions. The recently developed extractive electrospray ionization time-of-f ...

2021

A gas phase approach for glycan analysis: Combining ultrahigh-resolution ion mobility spectrometry with cryogenic vibrational spectroscopy

Ahmed Ben Faleh

The last decades have been punctuated by the development of revolutionary analytical technologies that have enabled the analysis of biomolecular structures and unraveled the roles they play in biological systems. However, certain classes of biomolecules re ...

EPFL2021

Analyzing glycans cleaved from a biotherapeutic protein using a combination of ion mobility spectrometry and cryogenic ion spectroscopy

Natalia Yalovenko

The characterization of biomolecules plays a central role in biomedical research. The development of state-of-the-art technologies is needed to make such analyses faster, more sensitive, and more accurate. While mass spectrometry continues to play a centra ...

EPFL2021

Siloxane compounds in biogas from manure and mixed organic waste: Method development and speciation analysis with GC-ICP-MS

Christian Ludwig, Debora Foppiano, Mohamed Tarik

A novel method for the determination of linear and cyclic siloxane compounds (L2, L3, D3, D4, D5, and D6) in biogas was developed by combining gas chromatography (GC) with inductively coupled plasma mass spectrometry (ICP-MS). Using a continuous liquid que ...

2020

Selection of Water-Soluble Chitosan by Microwave-Assisted Degradation and pH-Controlled Precipitation

Sandrine Gerber, Céline Marie Anne Journot, Yann Lavanchy, Laura Camille Louise Nicolle

In the field of gene therapy, chitosan (CS) gained interest for its promise as a non-viral DNA vector. However, commercial sources of CS lack precise characterization and do not generally reach sufficient solubility in aqueous media for in vitro and in viv ...

2020

Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes

Didier Trono, Marion Leleu, Evaristo Jose Planet Letschert, George Coukos, Ioannis Xenarios, Laia Simo Riudalbas, Delphine Yvette L Grun, Alexandre Harari, Markus Müller, Lin Zhang, Marion Arnaud, Florian Huber

Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable of mediating T cell-based tumor rejection still face important challenges. Recent studies suggest that non-canonical tumor-specific HLA peptides derived from annotated ...

Nature Research2020

Reversible Oxygen Sensing Based on Multi-Emission Fluorescence Quenching

Esther Amstad, Akin Gürsoy, Efe Armagan, Claudio Toncelli, René M. Rossi

Oxygen is ubiquitous in nature and it plays a key role in several biological processes, such as cellular respiration and food deterioration, to name a few. Currently, reversible and non-destructive oxygen sensing is usually performed with sensors produced ...

2020

First Observation of Excited Omega(-)(b) States

Christoph Frei, Peter Clarke, Aurelio Bay, Minh Tâm Tran, Marc-Olivier Bettler, François Fleuret, Tatsuya Nakada, Guido Haefeli, Niko Neufeld, Olivier Schneider, Hans Dijkstra, Frédéric Teubert, Gerhard Raven, Mingkui Wang, Chitsanu Khurewathanakul, Frédéric Blanc, Matthew Needham, Axel Kuonen, Olivier Göran Girard, Liang Sun, Maxime Schubiger, Brice Emile Maurin, Thibaud Humair, Hang Yin, Xiaoxue Han, Greig Alan Cowan, Paolo Durante, Jessica Prisciandaro, Guillaume Max Pietrzyk, Matthieu Philippe Luther Marinangeli, Vladislav Balagura, Lino Ferreira Lopes, Zhirui Xu, Mark Tobin, Victor Coco, Violaine Bellée, Mirco Dorigo, Yu Zheng, Vincenzo Battista, Maurizio Martinelli, Tommaso Colombo, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,

Development and performance evaluation of a high mass resolution time of flight laser ablation ionisation mass spectrometer

Reto Wiesendanger

This thesis contributes to the field of analytical chemistry of solid samples by introducing a new instrument with unprecedented performance characteristics and analytical capabilities. The instrument is based on the laser ablation and ionisation time-of-f ...

EPFL2019

Quantification of THC in Cannabis plants by fast-HPLC-DAD: A promising method for routine analyses

Christophe Roussel, Céline Burnier

Nowadays, Gas Chromatography Mass Spectrometry (GC-MS) is mainly used in forensic sciences but suffers from limitations when the analysed compounds are thermally instable as it is the case for THC-A (Tetrahydrocannabinolic Acid) which is converted into Del ...

ELSEVIER SCIENCE BV2019

The pro-apoptotic effect of a Terpene-rich Annona cherimola leaf extract on leukemic cell lines

Rita Sarkis, Maria Younes

Background The edible fruit Annona cherimola has previously shown many nutritional and medicinal properties. The current study evaluates the anti-cancer and anti-proliferative properties of Annona cherimola ethanolic leaf extract (AELE) on Acute Myeloid Le ...

2019

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Guido Andreassi

Maxim Borisyak

Dipanwita Dutta

Plamen Hristov Hopchev

Maria Elena Stramaglia

Ana Bárbara Rodrigues Cavalcante

Federico Leo Redi

Michel De Cian

Sebastian Schulte

Veronica Sølund Kirsebom

Aravindhan Venkateswaran

Luis Miguel Garcia Martin

Giovanni Carboni

Zheng Wang

We report four narrow peaks in the Xi K-0(b)- mass spectrum obtained using pp collisions at center-of-mass energies of 7, 8, and 13 TeV, corresponding to a total integrated luminosity of 9 fb(-1) recorded by the LHCb experiment. Referring to these states b ...

AMER PHYSICAL SOC2020