Publication

Metallierung und Abwandlung funktionell substituierter Alkene

Manfred Schlosser
1974
Journal Articles

Abstract

1,4-Dienes, vinyl ethers, allyl ethers, allyl thio ethers, and propenethiolates were metalated by BuLi in the presence of an activator such as KOCMe3. Since the solvent, the counter-ion, or the temp. may be varied before subsequent treatment with an electrophile, the crit. ratio of direct vs. vinylogous attack (substitution at the a- or g-position, resp.) can be adjusted within large limits. Stereoselectivity was also achieved. [on SciFinder (R)]

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Manfred Schlosser
1974
Journal Articles

Abstract

Official source

Related concepts (31)

Electrophile

In chemistry, an electrophile is a chemical species that forms bonds with nucleophiles by accepting an electron pair. Because electrophiles accept electrons, they are Lewis acids. Most electrophiles are positively charged, have an atom that carries a partial positive charge, or have an atom that does not have an octet of electrons. Electrophiles mainly interact with nucleophiles through addition and substitution reactions.

Solvent

A solvent (from the Latin solvō, "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution. A solvent is usually a liquid but can also be a solid, a gas, or a supercritical fluid. Water is a solvent for polar molecules and the most common solvent used by living things; all the ions and proteins in a cell are dissolved in water within the cell. Major uses of solvents are in paints, paint removers, inks, and dry cleaning. Specific uses for organic solvents are in dry cleaning (e.

Substitution reaction

A substitution reaction (also known as single displacement reaction or single substitution reaction) is a chemical reaction during which one functional group in a chemical compound is replaced by another functional group. Substitution reactions are of prime importance in organic chemistry. Substitution reactions in organic chemistry are classified either as electrophilic or nucleophilic depending upon the reagent involved, whether a reactive intermediate involved in the reaction is a carbocation, a carbanion or a free radical, and whether the substrate is aliphatic or aromatic.

Related publications (1)

Metallierung und Abwandlung funktionell substituierter Alkene

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Living polymers: Ab initio molecular dynamics study of the initiation step in the polymerization of isoprene induced by ethyl lithium