Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

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Visualization of organelles and their interactions with other features in the native cell remains a challenge in modern biology. We have introduced cryo-scanning transmission electron tomography (CSTET), which can ac-cess 3D volumes on the scale of 1 micro ...

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A microsecond time-resolved version of cryo-electron microscopy (cryo-EM) has recently been introduced to enable observation of the fast conformational motions of proteins. The technique involves locally melting a cryo sample with a laser beam to allow the ...

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In most metazoans, centrioles are lost during oogenesis, ensuring that the zygote is endowed with the correct number of two centrioles, which are paternally contributed. How centriole architecture is dismantled during oogenesis is not understood. Here, we ...

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Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography

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Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS-1

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Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Graphene nanoplatelets promoted CoO-based catalyst for low temperature CO2 methanation reaction