Role of arginase pathway in response to shear stress: new potential therapeutic targets for atherosclerosis?

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This work introduces a new methodology to predict the fatigue life of viscoelastic materials by considering the creep effect on fatigue behavior under the concurrent effects of stress level, stress ratio, and temperature. The model established based on the ...

Localized sources of morphogens, called signalling centres, play a fundamental role in coordinating tissue growth and cell fate specification during organogenesis. However, how these signalling centres are established in tissues during embryonic developmen ...

Several boreholes were drilled for site comparison of a deep geological repository (DGR) in Northern Switzerland. The main target of the exploration program was the >100m thick Opalinus Clay, the designated host rock encountered at approximately 450 to 100 ...

This data package supports the publication 'Complexity of crack front geometry enhances toughness of brittle solids' by Xinyue Wei, Chenzhuo Li, Cían McCarthy, and John M. Kolinski Nature physics (2024) - https://doi.org/10.1038/s41567-024-02435-x DOI: 1 ...

We update the publicly available weak lensing shear measurement algorithm pyRRG for the JWST, and apply it to UNCOVER DR1 imaging of galaxy cluster Abell 2744. At short wavelengths (

Reinforced concrete flat slabs consist of a continuous, thin concrete plate that rests on a grid of columns. The supporting surface of the columns is very small compared to the floor plan dimensions, leading to concentrations of shear forces near the colum ...

Earthquakes i.e. frictional ruptures, are commonly described by singular solutions of shear crack motions. These solutions assume a square root singularity order around the rupture tip and a constant shear stress value behind it, implying scale-independent ...

The number of transient operations in hydraulic machinery connected to power grid, notably start-ups and shut-downs, has observed a substantial increase in recent decades, primarily driven by the global shift toward intermittent renewable energy sources. S ...

The present study focuses on enhancing the seismic resistance of existing masonry structures. To that aim, the use of fiber-reinforced polymer (FRP) strengthening serves to improve structural behaviour by attaching FRP strips to the masonry walls. Despite ...

While understanding the shear strength of stone masonry structures is important for the design and the mainte- nance, we still lack computational tools for predicting the strength as a function of the stone layout. Here we implement an end-to-end image bas ...

We study the flow stability and spatiotemporal spectral dynamics of cellulose nanocrystal (CNC) suspensions in a custom Taylor-Couette flow cell using the intrinsic shear induced birefringence and liquid crystalline properties of CNC suspensions for flow v ...

Offshore pipelines that transport hydrocarbons under high pressure and high temperature are usually thermally insulated to maintain an elevated temperature and prevent any heat loss to the surroundings. However, the temperatures at the outer-wall of the pi ...

Wyoming-type bentonite is one of the materials to be used as part of the Engineered Barrier System (EBS) in deep geological disposal facilities for the safe disposal of spent nuclear fuel.In the KBS-3 type repository, the canisters containing the spent fue ...

The hydromechanical response of a Wyoming-type bentonite (MX-80) and its interface with steel was studied in terms of shear resistance under different hydration levels. A series of shear tests under constant normal stress were performed in total suction co ...

We investigate the fluid-driven growth of a shear crack along a frictional discontinuity and its transition to hydraulic fracturing (sometimes referred to as hydraulic jacking) under plane-strain conditions. We focus on the case of a constant friction coef ...

The stress state is an important parameter in terms of both earthquake nucleation and rupture. Here, a new stimulation technique is proposed for Enhanced Geothermal Systems (EGSs), which have previously been burdened with a number of high-profile incidence ...

Lay Summary The aim of this study is to determine whether using polygenic risk scores improves the prediction of atherosclerotic cardiovascular disease risk when combined with clinical scores currently recommended by European and US guidelines on cardiovas ...

Superionics are fascinating materials displaying both solid- and liquid-like characteristics: as solids, they respond elastically to shear stress; as liquids, they display fast-ion diffusion at normal conditions. In addition to such scientific interest, su ...

Geotechnical problems with total stress changes occurring rapidly relative to the soil consolidation time can be conveniently addressed using an effective stress-based approach. For saturated states, analytical formulations of pore-pressure coefficients ad ...

Bio-based resins, obtained from renewable raw materials, are a more sustainable alternative to oil-based resins for fiber-reinforced polymer (FRP) composites. The incorporation of lignin in those resins has the potential to enhance their performance. This ...

Role of arginase pathway in response to shear stress: new potential therapeutic targets for atherosclerosis?

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A novel fatigue life prediction methodology based on energy dissipation in viscoelastic materials, synergistic effects of stress level, stress ratio, and temperature

Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

Insights from an extensive triaxial testing campaign on a shale for comparative site characterization of a deep geological repository

Dataset for "Complexity of crack front geometry enhances toughness of brittle solids"

Weak gravitational lensing measurements of Abell 2744 using JWST and shear measurement algorithm pyRRG-JWST

Shear and steel-fibre reinforcement for the punching resistance of flat slabs at internal and edge columns

Frictional weakening leads to unconventional singularities during dynamic rupture propagation

On the prediction of the induced damage by the start-up sequence of Francis turbines: On operational resilience framework

Numerical Modeling of FRP-Strengthened Masonry Structures Using Equivalent Frame Models

Micro modeling of irregular stone masonry walls using mathematical programming

Painting Taylor vortices with cellulose nanocrystals: Suspension flow supercritical spectral dynamics

Drained Clay-Pipe Interface Resistance at Low Normal Stresses and Elevated Temperatures

Shear strength and shear stiffness analysis of compacted Wyoming-type bentonite

Hydro-mechanichal characterisation of bentonite/steel interfaces

Shearing and opening of a pre-existing discontinuity in response to fluid injection

Single-Well Pore Pressure Preconditioning for Enhanced Geothermal System Stimulation

Combining European and US risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study

Solids that are also liquids: elastic tensors of superionic materials

Pore-pressure coefficients for unsaturated soils: generalized effective stress approach

Incorporation of Lignin in Bio-Based Resins for Potential Application in Fiber-Polymer Composites