Publication

Genomic studies indicate a novel combination therapy for follicular lymphoma COMMENT

Elisa Oricchio
2021
Journal Articles

Abstract

Follicular lymphoma (FL) is an incurable form of B-cell lymphoma. Genomic alterations that inactivate RB signaling are surprisingly common in indolent FL. We show that FLs that are positive for phosphorylated RB respond to dual CDK4/BCL2 inhibition. Our results imply that RB phosphorylation identifies patients likely to benefit from such dual intervention.

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Genomic studies indicate a novel combination therapy for follicular lymphoma COMMENT

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