Publications related to MRI of animal models of developmental disorders and translation to human imaging

Related publications (36)

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Amnestic Syndrome in Memory Clinics: Similar Morphological Brain Patterns in Older Adults with and without Alzheimer's Disease

Alessandra Griffa, Bénédicte Marie Maréchal, Tommaso Di Noto

Background: Amnestic syndrome of the hippocampal type (ASHT) in Memory Clinics is a presentation common to Alzheimer's disease (AD). However, ASHT can be found in other neurodegenerative disorders. Objective: To compare brain morphometry including hippocam ...

IOS PRESS2024

Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes

Tobias Kober, Tom Hilbert, Gian Franco Piredda

BACKGROUND AND PURPOSE: MS lesions exhibit varying degrees of axonal and myelin damage. A comprehensive description of lesion phenotypes could contribute to an improved radiologic evaluation of smoldering inflammation and remyelination processes. This stud ...

Amer Soc Neuroradiology2024

Inverse Problems in Pulse-Echo Ultrasound: Exploiting Coherence for Image Enhancement and Quantitative Imaging

Samuel Denys Beuret

Whereas pulse-echo ultrasound imaging relied on focused acoustic waves since its inception, the last two decades have seen the development of techniques based on unfocused waves, including ultrafast ultrasound imaging. In large part due to the emergence of ...

EPFL2024

Comparing various AI approaches to traditional quantitative assessment of the myocardial perfusion in [82Rb] PET for MACE prediction

Julien René Fageot, Adrien Raphaël Depeursinge

Assessing the individual risk of Major Adverse Cardiac Events (MACE) is of major importance as cardiovascular diseases remain the leading cause of death worldwide. Quantitative Myocardial Perfusion Imaging (MPI) parameters such as stress Myocardial Blood F ...

Nature Portfolio2024

Quantified interface chemistry and biophysics via water imaging

Sylvie Roke

High throughput wide-field second harmonic imaging enables the label-free imaging of interfacial (< 3 nm thick) water, with a spatial resolution of similar to 370 nm using similar to 100 ms acquisition times per image. The obtained interfacial orientationa ...

Spie-Int Soc Optical Engineering2024

The hindbrain and cortico-reticular pathway in adolescent idiopathic scoliosis

Bénédicte Marie Maréchal

AIM: To characterise the corticoreticular pathway (CRP) in a case -control cohort of adolescent idiopathic scoliosis (AIS) patients using high -resolution slice -accelerated readoutsegmented echo -planar diffusion tensor imaging (DTI) to enhance the discri ...

W B Saunders Co Ltd2024

Time-resolved imaging with SPAD detectors

Jiuxuan Zhao

With the capabilities such as single-photon detection, time stamping and high-speed acquisition, time-resolved imaging based on single-photon avalanche diode (SPAD) detectors has found significant applications across diverse domains, including but not limi ...

EPFL2023

Imaging system with silicon photomultipliers and method for operating thereof

Edoardo Charbon, Andrada Alexandra Muntean

The invention relates to an integrated imaging system comprising: - an array of analog photomultiplier elements - a plurality of submodules, each submodule having a number of the photomultiplier elements; - a plurality of time-to-digital converters each as ...

2023

Correlated-photon imaging at 10 volumetric images per second

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü, Paul Mos

The correlation properties of light provide an outstanding tool to overcome the limitations of traditional imaging techniques. A relevant case is represented by correlation plenoptic imaging (CPI), a quantum-inspired volumetric imaging protocol employing s ...

Nature Portfolio2023

Functional neuroimaging options for tinnitus

Patrick Karl Alois Neff

Background: The pathophysiology behind tinnitus is still not well understood. Different imaging methods help in the understanding of the complex relationships that lead to the perception of tinnitus.Objective: Herein, different functional imaging methods t ...

SPRINGER2023

Clinical feasibility and validation of the accelerated T2 mapping sequence GRAPPATINI in brain imaging

Tom Hilbert

Rationale and objectives: To prospectively evaluate feasibility and robustness of an accelerated T2 mapping sequence (GRAPPATINI) in brain imaging and to assess its synthetic T2-weighted images (sT2w) in comparison with a standard T2-weighted sequence (T2 ...

CELL PRESS2023

Integrated electronics for time-of-flight positron emission tomography photodetectors

Andrada Alexandra Muntean

Positron emission tomography is a nuclear imaging technique well known for its use in oncology for cancer diagnosis and staging. A PET scanner is a complex machine which comprises photodetectors placed in a ring configuration that detect gamma photons gen ...

EPFL2023

Stability of Image-Reconstruction Algorithms

Michaël Unser, Sebastian Jonas Neumayer, Pol del Aguila Pla

Robustness and stability of image-reconstruction algorithms have recently come under scrutiny. Their importance to medical imaging cannot be overstated. We review the known results for the topical variational regularization strategies ( ℓ2 and ℓ1 regulariz ...

2023

Harmonization of multi-scanner in vivo magnetic resonance spectroscopy: ENIGMA consortium task group considerations

Cristina Ramona Cudalbu Moldovan

Magnetic resonance spectroscopy is a powerful, non-invasive, quantitative imaging technique that allows for the measurement of brain metabolites that has demonstrated utility in diagnosing and characterizing a broad range of neurological diseases. Its impa ...

FRONTIERS MEDIA SA2023

Brain's Dynamic Functional Organization with Simultaneous EEG-fMRI Networks

Patricia Figueiredo, João Pedro Forjaco Jorge

The brain's functional networks can be assessed using imaging techniques like functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). Recent studies have suggested a link between the dynamic functional connectivity (dFC) captured by ...

SPRINGER INTERNATIONAL PUBLISHING AG2023

3D reconstruction of curvilinear one-dimensional objects viewed in transmission electron microscopy

Gulnaz Ganeeva

To obtain a more complete understanding of material microstructure at the nanoscale and to gain profound insights into their properties, there is a growing need for more efficient and precise methods that can streamline the process of 3D imaging using a tr ...

EPFL2023

From Nano to Macro An overview of the IEEE Bio Image and Signal Processing Technical Committee

Michaël Unser, Dimitri Nestor Alice Van De Ville, Michael Stefan Daniel Liebling

The Bio Image and Signal Processing (BISP) Technical Committee (TC) of the IEEE Signal Processing Society (SPS) promotes activities within the broad technical field of biomedical image and signal processing. Areas of interest include medical and biological ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Brain morphometry in older adults with and without dementia using extremely rapid structural scans

Tobias Kober, Tom Hilbert

T1-weighted structural MRI is widely used to measure brain morphometry (e.g., cortical thickness and subcortical volumes). Accelerated scans as fast as one minute or less are now available but it is unclear if they are adequate for quantitative morphometry ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2023

Accurate Diagnosis of Cortical and Infratentorial Lesions in Multiple Sclerosis Using Accelerated Fluid and White Matter Suppression Imaging

Tobias Kober

Objectives: The precise location of multiple sclerosis (MS) cortical lesions can be very challenging at 3 T, yet distinguishing them from subcortical lesions is essential for the diagnosis and prognosis of the disease. Compressed sensing-accelerated fluid ...

LIPPINCOTT WILLIAMS & WILKINS2023