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Dynamic connectivity of hippocampal parcels unveils vulnerability markers in offspring of bipolar patients

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Sensorimotor and social mechanisms of hallucinations in healthy participants and patients with Parkinson's Disease

Louis Philippe Albert

Most patients with Parkinson's disease (PD) are not only affected by motor symptoms (e.g., tremor, rigidity, bradykinesia), but also experience hallucinations. Importantly, hallucinations are a risk factor for a more rapid cognitive decline, dementia, and ...

EPFL2024

Sleep fingerprinting: Individual identification using sleep macro- and micro-architecture

Dimitri Nestor Alice Van De Ville

WILEY2022

Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis

Lijing Xin

Research in schizophrenia (SZ) emphasizes the need for new therapeutic approaches based on antioxidant/anti-inflammatory compounds and psycho-social therapy. A hallmark of SZ is a dysfunction of parvalbumin-expressing fast-spiking interneurons (PVI), which ...

2021

Longitudinal expression changes are weak correlates of disease progression in Huntington's disease

Irina Krier

Huntington's disease is a severe but slowly progressive hereditary illness for which only symptomatic treatments are presently available. Clinical measures of disease progression are somewhat subjective and may require years to detect significant change. T ...

OXFORD UNIV PRESS2020

Different emotional disturbances in two experimental models of temporal lobe epilepsy in rats

Maria del Carmen Sandi Perez

Affective symptoms such as anxiety and depression are frequently observed in patients with epilepsy. The mechanisms of comorbidity of epilepsy and affective disorders, however, remain unclear. Diverse models are traditionally used in epilepsy research, inc ...

Public Library of Science2012