Publications related to Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen

Related publications (6)

Estimated transmission dynamics of SARS-CoV-2 variants from wastewater are unbiased and robust to differential shedding

Tamar Kohn, Timothy R. Julian, Charles Zeng Gan

The COVID-19 pandemic has accelerated the development and adoption of wastewater-based epidemiology. Wastewater samples can provide genomic information for detecting and assessing the spread of SARS-CoV-2 variants in communities and for estimating importan ...

2025

The potential of metal–organic framework MIL-101(Al)–NH2 in the forefront of antiviral protection of cells via interaction with SARS-CoV-2 spike RBD protein and their antibacterial action mediated with hypericin and photodynamic treatment

Georges Wagnières, Jaroslava Joniová

The global pandemic of SARS-CoV-2 has highlighted the necessity for innovative therapeutic solutions. This research presents a new formulation utilising the metal–organic framework MIL-101(Al)–NH2, which is loaded with hypericin, aimed at addressing viral ...

2025

Joint host-pathogen genomic analysis identifies hepatitis B virus mutations associated with human NTCP and HLA class I variation

Jacques Fellay, Zhi Ming Xu, Dylan Lawless, Andreas Scheck, Olivier Noël Marie Naret, Arne Schneuing

Evolutionary changes in the hepatitis B virus (HBV) genome could reflect its adaptation to host -induced selective pressure. Leveraging paired human exome and ultra -deep HBV genome-sequencing data from 567 affected individuals with chronic hepatitis B, we ...

Cell Press2024

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Luqing Li, Michele De Palma, Nahal Mansouri, Ali Ghasemi, Alan Nicolas Thierry Guichard, Yahya Mohammadzadeh, Bruno Torchia

Dendritic cells (DCs) are antigen-presenting myeloid cells that regulate T cell activation, trafficking and function. Monocyte-derived DCs pulsed with tumor antigens have been tested extensively for therapeutic vaccination in cancer, with mixed clinical re ...

Nature Portfolio2023

Blood virosphere in febrile Tanzanian children

Jacques Fellay, Nicolas Jean Philippe Guex, Mary-Anne Hartley, Christian Iseli, Thomas Junier, Gasser Hassan Elbanna Abdelbaset Abdelrahman Elbanna

Viral infections are the leading cause of childhood acute febrile illnesses motivating consultation in sub-Saharan Africa. The majority of causal viruses are never identified in low-resource clinical settings as such testing is either not part of routine s ...

2021

Whole-exome Sequencing for the Identification of Rare Variants in Primary Immunodeficiency Genes in Children With Sepsis: A Prospective, Population-based Cohort Study

Jacques Fellay, Christian Axel Wandall Thorball, Alessandro Borghesi, Nimisha Chaturvedi, Samira Asgari

Background. The role of primary immunodeficiencies (PID) in susceptibility to sepsis remains unknown. It is unclear whether children with sepsis benefit from genetic investigations. We hypothesized that sepsis may represent the first manifestation of under ...

OXFORD UNIV PRESS INC2020