Publications related to Interferometric synthetic aperture microscopy for extended focus optical coherence microscopy

Related publications (35)

Subsurface fluorescence time-of-flight imaging using a large-format single-photon avalanche diode sensor for tumor depth assessment

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü

Significance: Fluorescence guidance is used clinically by surgeons to visualize anatomical and/or physiological phenomena in the surgical field that are difficult or impossible to detect by the naked eye. Such phenomena include tissue perfusion or molecula ...

SPIE Society of Photo-optical Instrumentation Engineers2024

Resolution in super-resolution microscopy — definition, trade-offs and perspectives

Aleksandra Radenovic, Suliana Manley

Super-resolution microscopy (SRM) is gaining popularity in biosciences; however, claims about optical resolution are contested and often misleading. In this Viewpoint, experts share their views on resolution and common trade-offs, such as labelling and pos ...

2024

Combining X-ray micro-CT and microscopy-based images of two lianas species to derive structural, mechanical and functional relationships

Alexandre Buttler, Anastasios Vassilopoulos, Pascal Turberg, Claudine Bettina Karlen

This paper presents a biomechanical study of stems of two liana species, Clematis vitalba and Vitis vinifera, investigates the mechanical performance of these two liana species and attempts to enhance the understanding of structure-function relationships. ...

2024

Community-developed checklists for publishing images and image analyses

Arne Seitz

Images document scientific discoveries and are prevalent in modern biomedical research. Microscopy imaging in particular is currently undergoing rapid technological advancements. However, for scientists wishing to publish obtained images and image-analysis ...

Nature Publishing Group2023

Practical computational imaging by use of spatiotemporal light modulation: from simulations to applications in biological microscopy

François Thierry M Marelli

Optical microscopy is an essential tool for biologists, who are often faced with the need to overcome the spatial and temporal resolution limitations of their devices to capture finer details. As upgrading imaging hardware is expensive, computational metho ...

EPFL2023

Single-shot Kramers-Kronig complex orbital angular momentum spectrum retrieval

Camille Sophie Brès, Jianqi Hu

Orbital angular momentum (OAM) spectrum diagnosis is a fundamental building block for diverse OAM-based systems. Among others, the simple on-axis interferometric measurement can retrieve the amplitude and phase information of complex OAM spectra in a few s ...

SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS2023

Exploring Novel Modalities for Optical Diffraction Tomography

Amirhossein Saba Shirvan

In the past decade, optical diffraction tomography has gained a lot of attention for its ability to create label-free three-dimensional (3D) images of the refractive index distribution of biological samples using scattered fields measured through holograph ...

EPFL2023

High sensitivity, incoherent differential imaging

Chiara Bonati

Microscopic visualisation of optically transparent samples has been a topic of interest for several decades. Features such as density or chemical composition can influence the optical phase of transmitted light, and phase contrast can reveal these structur ...

EPFL2022

Advanced Techniques in Optical Diffraction Tomography

Ahmed Bassam Sayed Ayoub Mohamed Emam

In this thesis, we study the 3 challenges described above. First, we study different reconstruction techniques and assess the fidelity of each reconstruction results by means of structured illumination and phase conjugation. By reconstructing the 3D refrac ...

EPFL2022

Pixel super-resolution with spatially entangled photons

Edoardo Charbon, Jiuxuan Zhao

Pixelation is common in quantum imaging systems and limit the image spatial resolution. Here, the authors introduce a pixel super-resolution approach based on measuring the full spatially-resolved joint probability distribution of spatially-entangled photo ...

Nature Portfolio2022

Event-driven acquisition for content-enriched microscopy

Suliana Manley, Dora Mahecic, Martin Weigert, Juliette Griffie, Chen Zhang, Willi Leopold Stepp

Event-driven acquisition uses neural-network-based recognition of specific biological events to trigger switching between slow and fast super-resolution imaging, enriching the capture of interesting events with high spatiotemporal resolution. A common goal ...

Nature Publishing Group2022

Experimental demonstration of dynamic spatiotemporal structured beams that simultaneously exhibit two orbital angular momenta by combining multiple frequency lines, each carrying multiple Laguerre-Gaussian modes

Tobias Kippenberg, Maxim Karpov, Zhe Zhao

In general, there are different, relatively independent forms of orbital angular momenta at a given propagation distance, which might exhibit different dynamic spatial characteristics. One type involves a beam with a helical phase-front that rotates around ...

Optica Publishing Group2022

The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

Giorgio Margaritondo, Lin Yang

Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ra ...

Nature Portfolio2022

Generation of OAM-carrying space-time wave packets with time-dependent beam radii using a coherent combination of multiple LG modes on multiple frequencies

Tobias Kippenberg, Maxim Karpov, Zhe Zhao

Space-time (ST) wave packets, in which spatial and temporal characteristics are coupled, have gained attention due to their unique propagation characteristics, such as propagation invariance and tunable group velocity in addition to their potential ability ...

Optica Publishing Group2022

Optical Diffraction Tomography Using Nearly In-Line Holography with a Broadband LED Source

Demetri Psaltis, Abhijit Roy

We present optical tomography methods for a 3D refractive index reconstruction of weakly scattering objects using LED light sources. We are able to record holograms by minimizing the optical path difference between the signal and reference beams while sepa ...

MDPI2022

Optical microscopy gets down to angstroms

Suliana Manley, Giorgio Tortarolo

Super-resolution microscopy at angstrom precision could pave the way to optical structural biology in cells. ...

NATURE PORTFOLIO2022

Ultrafast Transverse Modulation of Free Electrons by Interaction with Shaped Optical Fields

Phoebe Marie Tengdin, Fabrizio Carbone, Thomas La Grange, Ivan Madan, Giovanni Maria Vanacore, Simone Gargiulo, Francesco Barantani, Alexey Sapozhnik, Veronica Leccese

Spatiotemporal electron-beam shaping is a bold frontier of electron microscopy. Over the past decade, shaping methods evolved from static phase plates to low-speed electrostatic and magnetostatic displays. Recently, a swift change of paradigm utilizing lig ...

AMER CHEMICAL SOC2022

Large-Format Time-Gated SPAD Cameras for Real-Time Phasor-Based FLIM

Arin Can Ülkü

Fluorescence lifetime imaging microscopy (FLIM) is an imaging modality often used to monitor biochemical properties of a cell or a tissue. In addition to conventional fluorescence microscopy features, such as selective labeling and non-invasiveness, FLIM e ...

EPFL2021

Polarization-sensitive optics diffraction tomography

Demetri Psaltis, Joowon Lim, Amirhossein Saba Shirvan

Polarization of light has been widely used as a contrast mechanism in two-dimensional (2D) microscopy and also in some three-dimensional (3D) imaging modalities. In this paper, we report the 3D tomographic reconstruction of the refractive index (RI) tensor ...

2021

Structured light generation by refractive-diffractive micro optical array illuminators

Maryam Yousefi

Structured light generation having broad applications in different optical fields, is the topic of this thesis. Our structured light generation strategy is based on applying periodic microoptical elements at the refraction-diffraction limit, under a focuse ...

EPFL2021