Light dosimetry for photodynamic therapy in the esophagus

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Background aims: Age-related macular degeneration (AMD) is the most common cause of blindness in elderly patients within developed countries, affecting more than 190 million worldwide. In AMD, the retinal pigment epithelial (RPE) cell layer progressively d ...

Metabolic changes precede malignant histology. However, it remains unclear whether detectable characteristic metabolome exists in esophageal squamous cell carcinoma (ESCC) tissues and biofluids for early diagnosis. Here, we conduct NMR- and MS-based metabo ...

In the last decade, organoid technology has become a cornerstone in cancer research. Organoids are long-term primary cell cultures, usually of epithelial origin, grown in a three-dimensional (3D) protein matrix and a fully defined medium. Organoids can be ...

Plasmonic photochemistry has a large potential to replace energy-intensive chemical processes with low-temperature, low-pressure light-driven chemical reactions. Plasmonic nanostructures have emerged as promising photocatalysts with exceptional and tunable ...

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BRCA2 and RAD51 are two proteins that play a central role in homologous recombination (HR) and DNA double strand break (DSB) repair. BRCA2 assists RAD51 fibrillation and defibrillation through binding with its eight BRC repeats, with BRC4 being one of the ...

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Activin-A, a transforming growth factor ê µ family member, is a pleiotropic cytokine with diverse functions in development, fertility, adult tissue homeostasis, and aging. Accordingly, deregulation of Activin-A signaling has been associated with many patho ...

Light dosimetry for photodynamic therapy in the esophagus

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Clinically compliant cryopreservation of differentiated retinal pigment epithelial cells

NMR and MS reveal characteristic metabolome atlas and optimize esophageal squamous cell carcinoma early detection

Next-Generation Modeling of Cancer Using Organoids

Plasmonic Nanostructures for Photocatalysis: Material, Photonic and Electronic Effects

CellCharter reveals spatial cell niches associated with tissue remodeling and cell plasticity

Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Elucidating and modulating regulatory pathways so as to reprogram the immunosuppressive tumor microenvironment for therapeutic benefit

Cancer hallmarks intersect with neuroscience in the tumor microenvironment

Medical and Personal Characteristics Can Predict the Risk of Lung Metastasis

Preomic profile of BxPC-3 cells after treatment with BRC4

Balancing the Nanoscale Organization in Multivalent Materials for Functional Inhibition of the Programmed Death-1 Immune Checkpoint

Translational screening platform to evaluate chemotherapy in combination with focal therapy for retinoblastoma

The physics of 3D printing with light

Tumor dormancy: EMT beyond invasion and metastasis

The mesoglea buffers the physico-chemical microenvironment of photosymbionts in the upside-down jellyfish Cassiopea sp

Multiomic analysis of HER2-enriched and AR-positive breast carcinoma with apocrine differentiation and an oligometastatic course: a case report

Mechanical Immunoengineering of T Cells for Enhanced Cancer Immunotherapy

Microfluidic T Cell Selection by Cellular Avidity

Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation

Immunosuppressive roles of Activin-A in melanoma and characterization of its precursor cleavage