Publications related to Neurobiological and metabolic basis of motivation and effort-based decision-making - A human 1H-MRS, fMRI and machine learning study

Related publications (47)

Automated Ensemble Multimodal Machine Learning for Healthcare

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single modality. This stan ...

2025

Non-asymptotic performance of social machine learning under limited data

Ali H. Sayed, Virginia Bordignon, Mert Kayaalp, Ping Hu

This paper studies the probability of error associated with the social machine learning framework, which involves an independent training phase followed by a cooperative decision-making phase over a graph. This framework addresses the problem of classifyin ...

2025

Solving the Cold-Start Problem for the Edge: Clustering and Adaptive Deep Learning for Emotion Detection

José Angel Miranda Calero

Designing AI-based applications personalized to each user's behavior presents significant challenges due to the cold start problem and the impracticality of extensive individual data labeling. These challenges are further compounded when deploying such app ...

IEEE2025

Adaptive Test-Time Learning Under Domain Shift: From Augmentation to Prolonged Adaptation

Devavrat Tomar

Deep neural networks often fail to generalize when deployed in dynamic and unpredictable real-world environments, where data distributions at test time can differ significantly from those encountered during training. Since simulating all possible distribut ...

EPFL2025

Fast 3D 31P B1+ mapping with a weighted stack of spiral trajectory at 7 T

Salomé Sophie Célestine Baup, Lijing Xin, Katarzyna Pierzchala, Daniel Wenz, Mark Stephan Widmaier, Ying Xiao, Zhiwei Huang, Antonia Kaiser

Purpose: Phosphorus MRS (31P MRS) enables noninvasive assessment of energy metabolism, yet its application is hindered by sensitivity limitations. To overcome this, often high magnetic fields are used, leading to challenges such as spatial (Formula present ...

Wiley2025

An integrative computational modeling approach for Drosophila motor control

Pembe Gizem Ozdil

Animal motor control arises from the intricate interplay between neural circuits, biomechanics, and sensory feedback. Deciphering how these components interact is essential for uncovering the fundamental principles of movement generation. This dissertation ...

EPFL2025

Accelerating MoE Model Inference with Expert Sharding

André Loureiro Espírito Santo, Anne-Marie Kermarrec, Rafael Pereira Pires, Marinus Abraham de Vos, Milos Vujasinovic

Mixture of experts (MoE) models achieve state-of-the-art results in language modeling but suffer from inefficient hardware utilization due to imbalanced token routing and communication overhead. While prior work has focused on optimizing MoE training and d ...

Association for Computing Machinery2025

The visuomotor transformations underlying target-directed behavior

Thomas Ka Chung Lam

The visual system can process diverse stimuli and make the decision to execute appropriate behaviors, but it remains unclear where and how this transformation takes place. Innate visually evoked behaviors such as hunting, freezing, and escape are thought t ...

2025

Cerebellar dysfunction in frontotemporal dementia: intra-cerebellar pathology and cerebellar network degeneration

Bernard Schneider

Background: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share overlapping clinical, genetic, and neuroimaging features; a spectrum of conditions commonly referred to as the ALS-FTD continuum. The majority of imaging studies focus ...

2025

Reliable data-driven decision-making through optimal transport

Bahar Taskesen

Decision-making permeates every aspect of human and societal development, from individuals' daily choices to the complex decisions made by communities and institutions. Central to effective decision-making is the discipline of optimization, which seeks th ...

EPFL2024

Age-associated nicotinamide adenine dinucleotide decline drives CAR-T cell failure

Johan Auwerx

Chimeric antigen receptor (CAR) T cell therapy is one of the most promising cancer treatments. However, different hurdles are limiting its application and efficacy. In this context, how aging influences CAR-T cell outcomes is largely unknown. Here we show ...

Springer Science and Business Media LLC2025

The hindbrain and cortico-reticular pathway in adolescent idiopathic scoliosis

Bénédicte Marie Maréchal

AIM: To characterise the corticoreticular pathway (CRP) in a case -control cohort of adolescent idiopathic scoliosis (AIS) patients using high -resolution slice -accelerated readoutsegmented echo -planar diffusion tensor imaging (DTI) to enhance the discri ...

W B Saunders Co Ltd2024

Let There Be Light: Robust Lensless Imaging Under External Illumination With Deep Learning

Stefan Christian Peters, Martin Vetterli, Eric Bezzam

Lensless cameras relax the design constraints of traditional cameras by shifting image formation from analog optics to digital post-processing. While new camera designs and applications can be enabled, lensless imaging is very sensitive to unwanted interfe ...

IEEE2025

Subcortical correlates of consciousness with human single neuron recordings

Olaf Blanke, Fosco Bernasconi, Nathan Quentin Faivre, Michael Eric Anthony Pereira

Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...

2024

Unraveling behavior and cortical signals to guide the development of soft neuroprostheses for auditory restoration and spreading depolarization

Emilie Cornelia Maria Revol

Neuroprostheses have been used clinically for decades, to help restore or preserve brain functions, when pharmaceutical treatments are inefficient. Although great progress in the field has been made over the years to interface with the nervous system, surf ...

EPFL2024

Single-cell epigenomic reconstruction of developmental trajectories from pluripotency in human neural organoid systems

Fides Zenk

Cell fate progression of pluripotent progenitors is strictly regulated, resulting in high human cell diversity. Epigenetic modifications also orchestrate cell fate restriction. Unveiling the epigenetic mechanisms underlying human cell diversity has been di ...

Nature Portfolio2024

Safety, tolerability and blinding efficiency of non-invasive deep transcranial temporal interference stimulation: first experience from more than 250 sessions

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Elena Beanato, Pierre Theopistos Vassiliadis, Fabienne Windel

Objective. Selective neuromodulation of deep brain regions has for a long time only been possible through invasive approaches, because of the steep depth-focality trade-off of conventional non-invasive brain stimulation (NIBS) techniques. Approach. An appr ...

Iop Publishing Ltd2024

An immersive virtual reality tool for assessing left and right unilateral spatial neglect

Olaf Blanke, Andrea Serino, Roberta Ronchi

The reported rate of the occurrence of unilateral spatial neglect (USN) is highly variable likely due to the lack of validity and low sensitivity of classical tools used to assess it. Virtual reality (VR) assessments try to overcome these limitations by pr ...

Wiley2024

Hearing structure in music: An empirical inquiry into listening as representation and processing

Gabriele Cecchetti

As a universal expression of human creativity, music is capable of conveying great subtlety and complexity. Crucially, this complexity is not encoded in the score or in the sounds, but is rather construed in the mind of the listener in the form of nuanced ...

EPFL2024

Unveiling the complexity of learning and decision-making

Wei-Hsiang Lin

Reinforcement learning (RL) is crucial for learning to adapt to new environments. In RL, the prediction error is an important component that compares the expected and actual rewards. Dopamine plays a critical role in encoding these prediction errors. In my ...

EPFL2024