Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Publication

Anhydrous Conditions Enable the Catalyst-Free Carboxylation of Aromatic Alkynes with CO2 under Mild Conditions

Paul Joseph Dyson, Marinella Mazzanti, Felix Daniel Bobbink, Davide Toniolo
2020
Journal Articles

Abstract

The direct carboxylation of aromatic alkynes with CO2, a cheap and widely available C1 source, is the most attractive method for the synthesis of carboxylic acids. Here we show that direct carboxylation of terminal alkynes can be simply performed in near-quantitative yield in four hours with anhydrous Cs2CO3 under mild conditions without need of a metal catalyst.

Official source

https://infoscience.epfl.ch/entities/publication/af1d52d8-eb85-487d-a3e3-1e580e1d5ce5

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Paul Joseph Dyson, Marinella Mazzanti, Felix Daniel Bobbink, Davide Toniolo
2020
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/af1d52d8-eb85-487d-a3e3-1e580e1d5ce5

About this result

Related concepts (25)

Alkyne

Acetylene Propyne 1-Butyne In organic chemistry, an alkyne is an unsaturated hydrocarbon containing at least one carbon—carbon triple bond. The simplest acyclic alkynes with only one triple bond and no other functional groups form a homologous series with the general chemical formula . Alkynes are traditionally known as acetylenes, although the name acetylene also refers specifically to , known formally as ethyne using IUPAC nomenclature. Like other hydrocarbons, alkynes are generally hydrophobic.

C4 carbon fixation

carbon fixation or the Hatch–Slack pathway is one of three known photosynthetic processes of carbon fixation in plants. It owes the names to the 1960s discovery by Marshall Davidson Hatch and Charles Roger Slack that some plants, when supplied with 14, incorporate the 14C label into four-carbon molecules first. fixation is an addition to the ancestral and more common carbon fixation. The main carboxylating enzyme in photosynthesis is called RuBisCO, which catalyses two distinct reactions using either (carboxylation) or oxygen (oxygenation) as a substrate.

Decarboxylation

Decarboxylation is a chemical reaction that removes a carboxyl group and releases carbon dioxide (CO2). Usually, decarboxylation refers to a reaction of carboxylic acids, removing a carbon atom from a carbon chain. The reverse process, which is the first chemical step in photosynthesis, is called carboxylation, the addition of CO2 to a compound. Enzymes that catalyze decarboxylations are called decarboxylases or, the more formal term, carboxy-lyases (EC number 4.1.1).

Related publications (28)

Anhydrous Conditions Enable the Catalyst-Free Carboxylation of Aromatic Alkynes with CO2 under Mild Conditions

Graph Chatbot

Novel Alkynylation Methods through the Combination of Hypervalent Iodine Reagents and Alkynyl-trifluoroborate Salts

Hypervalent Iodine: New Reagents and Functionalization of Peptides

Metabolic Performance and Fate of Electrons during Nitrate-Reducing Fe(II) Oxidation by the Autotrophic Enrichment Culture KS Grown at Different Initial Fe/N Ratios