Bodily Ownership : Tactile, Visual and Motor Mechanisms

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Neuronal correlates of goal-directed sensorimotor transformation in sensory, motor and higher-order cortical areas

Anastasiia Oryshchuk

An important function of the brain is to interpret incoming sensory information from the outside world to guide adaptive behavior. Understanding how and where sensory information is transformed into motor commands in a context- and learning-dependent manne ...

EPFL2023

Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Federico Amato

The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer therapy but only a fraction of patients benefits from this therapy. Model-informed drug development can be used to assess prognostic and predictive clinical factors or biomark ...

2023

Real-Time fMRI Neurofeedback: Methods and Application to Chronic Tinnitus

Nicolas Gninenko

In the last twenty years, advances in real-time functional magnetic resonance imaging (rt-fMRI) have offered exciting new tools to study the human brain. One of them, termed rt-fMRI neurofeedback (NF), has turned the MRI scanner environment into an interac ...

EPFL2022

Multi-centre classification of functional neurological disorders based on resting-state functional connectivity

Dimitri Nestor Alice Van De Ville, Jonas Richiardi

Background: Patients suffering from functional neurological disorder (FND) experience disabling neurological symptoms not caused by an underlying classical neurological disease (such as stroke or multiple sclerosis). The diagnosis is made based on reliable ...

ELSEVIER SCI LTD2022

Neuroscience robotics for controlled induction and real-time assessment of hallucinations

Olaf Blanke, Giulio Rognini, Fosco Bernasconi, Jevita Potheegadoo, Eva Blondiaux, Laurent Frédéric Jenni, Herberto Dhanis Pedro De Barros Camacho

Although hallucinations are important and frequent symptoms in major psychiatric and neurological diseases, little is known about their brain mechanisms. Hallucinations are unpredictable and private experiences, making their investigation, quantification a ...

Nature Publishing Group2022

Determining patterns of post-stroke motor recovery through longitudinal multimodal MRI: A step towards patient stratification

Julia Brügger

Motivated by the need for a better understanding of post-stroke recovery and new biomarkers to improve stroke patient stratification and outcomes, this thesis investigated structure-function coupling and its role in post-stroke recovery. Furthermore, in or ...

EPFL2022

Longitudinal interrogation of sympathetic neural circuits and hemodynamics in preclinical models

Victor Perez Puchalt, Jan Elaine Cuevas Soriano, Grégoire Courtine, Quentin Barraud, Jordan Squair, Matthieu Pierre Gautier, Loïs Thomas Romain Mahe, Rémi Bernard René Hudelle, Suje Amir

Neurological disorders, including spinal cord injury, result in hemodynamic instability due to the disruption of supraspinal projections to the sympathetic circuits located in the spinal cord. We recently developed a preclinical model that allows the ident ...

NATURE PORTFOLIO2022

Rituals of art and science to decompart(mentalize) knowledge

Bruno Herbelin

We here explore the potential of rituals in order to more fully comprehend the subjective mechanisms of listening, leading to a broader understanding of phenomenal consciousness (why and how do I know that I am experiencing something?). The originality of ...

Universitat Oberta de Catalunya, and ISEA lnternational2022

Impact of interhemispheric inhibition on bimanual movement control in young and old

Friedhelm Christoph Hummel, Takuya Morishita

Interhemispheric interactions demonstrate a crucial role for directing bimanual movement control. In humans, a well-established paired-pulse transcranial magnetic stimulation paradigm enables to assess these interactions by means of interhemispheric inhibi ...

SPRINGER2022

Emotion Recognition in a Multi-Componential Framework: The Role of Physiology

Gelareh Mohammadi

Emotions are rich and complex experiences involving various behavioral and physiological responses. While many empirical studies have focused on discrete and dimensional representations of emotions, these representations do not fully reconcile with recent ...

FRONTIERS MEDIA SA2022

Breathing control, brain, and bodily self-consciousness: Toward immersive digiceuticals to alleviate respiratory suffering

Olaf Blanke, Sophie Jacqueline Andrée Betka

Breathing is peculiar among autonomic functions through several characteristics. It generates a very rich afferent traffic from an array of structures belonging to the respiratory system to various areas of the brain. It is intimately associated with bodil ...

2022