Publication

Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

Nikolaos Stergiopoulos, Mikaël Nils Sturny, Maiia Bragina
2020
Journal Articles

Abstract

Background: The renin-angiotensin system (RAS) plays an important role in erectile function. The RAS contains 2 major axes: one deleterious, composed of ACE-Ang II-AT1 receptor, and another protective, composed of ACE2-Ang-(1-7)-Mas receptor. While aging is a well-known cause for development of male sexual disorders, little is known about local regulation of the RAS in age-related erectile dysfunction (ED).

Official source

https://infoscience.epfl.ch/entities/publication/ab45b092-7b8d-45ab-8ea8-02b19fb41e36

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Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis

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Pathophysiological role of the renin-angiotensin system on erectile dysfunction