SPICA: Swiss portal for immune cell analysis

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Infectious agents contribute significantly to the global burden of diseases through both acute infection and their chronic sequelae. We leveraged the UK Biobank to identify genetic loci that influence humoral immune response to multiple infections. From 45 ...

This document contains all the data and the details of the analysis used in the manuscript titled " Control of Ge island coalescence for the formation of nanowires on silicon." https://doi.org/10.1039/D3NH00573A ...

The advent of immunotherapy, such as immune checkpoint blockade (ICB) and adoptive transfer of cytotoxic lymphocytes, has transformed the clinical care of cancer. However, a significant proportion of patients are resistant to immunotherapy or experience re ...

Genome-wide chromatin conformation capture assays provide formidable insights into the spatial organization of genomes. However, due to the complexity of the data structure, their integration in multi-omics workflows remains challenging. We present data st ...

While largely neglected over decades during which adaptive immunity captured most of the attention, innate immune mechanisms have now become central to our understanding of immunology. Innate immunity provides the first barrier to infection in vertebrates, ...

Dataset corresponding to the following manuscript: Slagter, A., Setyadji, J.A., Vogt, E.L. et al. Nanoindentation Hardness and Modulus of Al2O3–SiO2–CaO and MnO–SiO2–FeO Inclusions in Iron. Metall Mater Trans A (2024). https://doi.org/10.1007/s11661-024-0 ...

Traditional cell cultures have long been fundamental to biological research, offering an alternative to animal models burdened by ethical constraints and procedural intricacies, often lacking relevance to human physiology and disease. Moreover, their inabi ...

This data set contains the data collected during the FNS project Green Piezo (Grant no. 179064) in association with the recent publication entitled “3D printing of customizable transient bioelectronics and sensors”. This work aims to study and demonstrate ...

This repository contains microphysics routines, scripts, and processed data from the Weather Research and Forecasting (WRF) model simulations presented in the paper "RaFSIP: Parameterizing ice multiplication in models using a machine learning approach", by ...

This paper presents a novel hybrid framework for generating and updating a synthetic population. We call it hybrid because it combines model-based and data-driven approaches. Existing generators produce a snapshot of synthetic data that becomes outdated ov ...

We propose a comparative study of three different methods aimed at optimizing existing groundwater monitoring networks. Monitoring piezometric heads in subsurface porous formations is crucial at regional scales to properly characterize the relevant subsurf ...

In this thesis we will present two results on global existence for nonlinear dispersive equations with data at or below the scaling regularity. In chapter 1 we take a probabilistic perspective to study the energy-critical nonlinear Schrödinger equation in ...

Heterochromatin loss and genetic instability enhance cancer progression by favoring clonal diversity, yet uncontrolled replicative stress leads to mitotic catastrophe and inflammatory responses that promote immune rejection. KRAB domain-containing zinc fin ...

This data package supports the publication 'Complexity of crack front geometry enhances toughness of brittle solids' by Xinyue Wei, Chenzhuo Li, Cían McCarthy, and John M. Kolinski Nature physics (2024) - https://doi.org/10.1038/s41567-024-02435-x DOI: 1 ...

Despite the widespread use of self-tracking technologies for promoting personal wellbeing, there is limited research on the monitoring of intimate data, particularly urine. To shed light on the design possibilities within this unexplored domain we designed ...

Numerous conductor designs for pulsed magnets based on High Temperature Superconductors (HTS), featuring stacks of tapes are currently being proposed. A major contribution to the AC losses is expected to be given by hysteresis losses. Several numerical mod ...

Image information about the state of a building after an earthquake, which can be collected without endangering the post-earthquake reconnaissance activities, can be used to reduce uncertainties in response predictions for future seismic events. This paper ...

Masonry aggregates, which emerged as layouts of cities and villages became denser, make up historical centres all over the world. In these aggregates, neighbouring structures may share structural walls that are joined at the interfaces by mortar or interlo ...

Human babies have a natural desire to interact with new toys and objects, through which they learn how the world around them works, e.g., that glass shatters when dropped, but a rubber ball does not. When their predictions are proven incorrect, such as whe ...

Background Excessive inflammation, hemolysis, and accumulation of labile heme play an essential role in the pathophysiology of multi-organ dysfunction syndrome (MODS) in sepsis. Alpha1-antitrypsin (AAT), an acute phase protein with heme binding capacity, i ...

SPICA: Swiss portal for immune cell analysis

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A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy

Data set for control of Ge island coalescence for the formation of nanowires on silicon

Exploration and modulation of mechanical cues for enhanced cancer immunotherapy

Orchestrating chromosome conformation capture analysis with Bioconductor

The conceptual foundations of innate immunity: Taking stock 30 years later

Nanoindentation hardness and modulus of Al2O3-SiO2-CaO and MnO-SiO2-FeO inclusions in iron

Accessible and highly observable gastrointestinal organoid model systems for studying host-pathogen interactions

Dataset for '3D printing of customizable transient bioelectronics and sensors'

Data and scripts for the RaFSIP scheme

Hybrid Simulator for Capturing Dynamics of Synthetic Populations

Data-driven statistical optimization of a groundwater monitoring network

Probabilistic and Deterministic Wellposedness for Low Regularity Dispersive Equations

A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress–Induced Inflammation

Dataset for "Complexity of crack front geometry enhances toughness of brittle solids"

Designing for Intimate Wellbeing: Aidee, a Qualitative Approach To Urine Home Monitoring

Validation and Application of Hysteresis Loss Model for HTS Stacks and Conductors for Fusion Applications

Reducing uncertainties in response predictions of earthquake-damaged masonry buildings using data from image-based inspection

Seismic Testing of Adjacent Interacting Masonry Structures – Analysis of a Blind Prediction

Seeking the new, learning from the unexpected: Computational models of surprise and novelty in the brain

Alpha1-antitrypsin improves survival in murine abdominal sepsis model by decreasing inflammation and sequestration of free heme