Electrochemical characterization of mechanically implanted boron doped diamond electrodes MI-BDD

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Walking naturally after spinal cord injury using a brain-spine interface

Léonie Asboth, Salif Axel Komi, Grégoire Courtine, Robin Jonathan Demesmaeker, Jocelyne Bloch, Sergio Daniel Hernandez, Henri Charles Alexandre Lorach, Edeny Baaklini, Jimmy James Ravier, Carmina Andrea Galvez Solano, Cathal John Harte, Grégory Didier Dumont, Thibault Jean Etienne Collin, Icare Sakr, Nadine Intering

A spinal cord injury interrupts the communication between the brain and the region of the spinal cord that produces walking, leading to paralysis(1,2). Here, we restored this communication with a digital bridge between the brain and spinal cord that enable ...

NATURE PORTFOLIO2023

Development of a Transient Neural Interface for Minimally Invasive Recording and Stimulation

Adele Fanelli

Transient electronics enabling devices to safely disappear in the environment can be applied not only in green electronics, but also in bioelectronic medicine. Neural implants able to degrade harmlessly inside the body eliminate the need for removal surger ...

EPFL2022

Conformable neural interfaces : from engineering stretchability at the micro-scale to translational applications

Florent-Valéry Coen

Recently, flexible and soft bioelectronic interfaces have been proposed as a solution to improve existing neural interfaces that currently present mechanical mismatch with the soft tissue. These are devices fabricated with thin polymeric or elastomeric bac ...

EPFL2022

Clinical neuroscience and neurotechnology: An amazing symbiosis

Silvestro Micera

In the last decades, clinical neuroscience found a novel ally in neurotechnologies, devices able to record and stimulate electrical activity in the nervous system. These technologies improved the ability to diagnose and treat neural disorders. Neurotechnol ...

2022

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Eleonora Borda

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

EPFL2022

The present and future of neural interfaces

Marcello Ienca

The 2020's decade will likely witness an unprecedented development and deployment of neurotechnologies for human rehabilitation, personalized use, and cognitive or other enhancement. New materials and algorithms are already enabling active brain monitoring ...

FRONTIERS MEDIA SA2022

Sense of agency for intracortical brain-machine interfaces

Olaf Blanke, Andrea Serino, Marco Solcà, Nathan Quentin Faivre, Pavo Orepic, Tommaso Enrico Bertoni

Intracortical brain-machine interfaces decode motor commands from neural signals and translate them into actions, enabling movement for paralysed individuals. The subjective sense of agency associated with actions generated via intracortical brain-machine ...

NATURE PORTFOLIO2022

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Nicolas Vachicouras, Stéphanie Lacour, Florent-Valéry Coen

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...

SPRINGER2022

Wireless Powering Efficiency of Deep-Body Implantable Devices

Anja Skrivervik, Denys Nikolayev, Mingxiang Gao

The wireless power transfer (WPT) efficiency to implanted bioelectronic devices is constrained by several frequency-dependent physical mechanisms. Recent works have developed several mathematical formulations to understand these mechanisms and predict the ...

Institute of Electrical and Electronics Engineers2022

Methods for acute and long-term imaging of the ventral nerve cord in behaving adult Drosophila

Laura Joan Hermans

Understanding how neural circuits remodel and adapt to animal behavior is a central theme in the field of Neuroscience. One strategy to reach this goal is to repeatedly record the same animal's neural circuits and observe how they adapt when facing differe ...

EPFL2022