Drug designDrug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient. In the most basic sense, drug design involves the design of molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will bind to it.
OpenAIOpenAI is an American artificial intelligence (AI) research laboratory consisting of the non-profit OpenAI, Inc. and its for-profit subsidiary corporation OpenAI, L.P.. OpenAI conducts research on artificial intelligence with the declared intention of developing "safe and beneficial" artificial general intelligence, which it defines as "highly autonomous systems that outperform humans at most economically valuable work".
TruthTruth is the property of being in accord with fact or reality. In everyday language, truth is typically ascribed to things that aim to represent reality or otherwise correspond to it, such as beliefs, propositions, and declarative sentences. Truth is usually held to be the opposite of falsehood. The concept of truth is discussed and debated in various contexts, including philosophy, art, theology, law, and science. Most human activities depend upon the concept, where its nature as a concept is assumed rather than being a subject of discussion, including journalism and everyday life.
Entropy (information theory)In information theory, the entropy of a random variable is the average level of "information", "surprise", or "uncertainty" inherent to the variable's possible outcomes. Given a discrete random variable , which takes values in the alphabet and is distributed according to : where denotes the sum over the variable's possible values. The choice of base for , the logarithm, varies for different applications. Base 2 gives the unit of bits (or "shannons"), while base e gives "natural units" nat, and base 10 gives units of "dits", "bans", or "hartleys".
Google SearchGoogle Search (also known simply as Google or Google.com) is a search engine provided and operated by Google. Handling more than 3.5 billion searches per day, it has a 92% share of the global search engine market. It is the most-visited website in the world. Additionally, it is the most searched and used search engine in the entire world. The order of search results returned by Google is based, in part, on a priority rank system called "PageRank".
OverfittingIn mathematical modeling, overfitting is "the production of an analysis that corresponds too closely or exactly to a particular set of data, and may therefore fail to fit to additional data or predict future observations reliably". An overfitted model is a mathematical model that contains more parameters than can be justified by the data. In a mathematical sense, these parameters represent the degree of a polynomial. The essence of overfitting is to have unknowingly extracted some of the residual variation (i.
Huntington's diseaseHuntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental/ psychiatric abilities. A general lack of coordination and an unsteady gait often follow. It is also a basal ganglia disease causing a hyperkinetic movement disorder known as chorea. As the disease advances, uncoordinated, involuntary body movements of chorea become more apparent.
Alarm clockAn alarm clock or alarm is a clock that is designed to alert an individual or group of individuals at a specified time. The primary function of these clocks is to awaken people from their night's sleep or short naps; they can sometimes be used for other reminders as well. Most alarm clocks make sounds; some make light or vibration. Some have sensors to identify when a person is in a light stage of sleep, in order to avoid waking someone who is deeply asleep, which causes tiredness, even if the person has had adequate sleep.
DNA repairDNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human cells, both normal metabolic activities and environmental factors such as radiation can cause DNA damage, resulting in tens of thousands of individual molecular lesions per cell per day. Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ability to transcribe the gene that the affected DNA encodes.
Productivity-improving technologiesThe productivity-improving technologies are the technological innovations that have historically increased productivity. Productivity is often measured as the ratio of (aggregate) output to (aggregate) input in the production of goods and services. Productivity is increased by lowering the amount of labor, capital, energy or materials that go into producing any given amount of economic goods and services. Increases in productivity are largely responsible for the increase in per capita living standards.
ClockA clock or chronometer is a device used to measure and indicate time. The clock is one of the oldest human inventions, meeting the need to measure intervals of time shorter than the natural units such as the day, the lunar month, and the year. Devices operating on several physical processes have been used over the millennia. Some predecessors to the modern clock may be considered "clocks" that are based on movement in nature: A sundial shows the time by displaying the position of a shadow on a flat surface.
Glossary of genetics (0–L)This glossary of genetics is a list of definitions of terms and concepts commonly used in the study of genetics and related disciplines in biology, including molecular biology, cell biology, and evolutionary biology. It is split across two articles: This page, Glossary of genetics (0–L), lists terms beginning with numbers and those beginning with the letters A through L. Glossary of genetics (M–Z) lists terms beginning with the letters M through Z.
