Publication

MECHANOSENSITIVE CELL SUBSTRATE

2006
Reports

Abstract

There are many questions in cell biology regarding the combined chemical-mechanical interactions between a cell and its surroundings. The mechanical feedback that a cell receives from its surroundings has a direct impact on its behaviour (eg. differentiation). We have developed free-standing cantilever substrates to investigate the forces exerted by cells. Cantilevers were fabricated using a gold lift-off method and released using a HF vapour etch of the underlying SiO2. By varying the thickness of the gold layer from 100nm to 450 nm -along with the cantilever dimensions- cantilevers with spring constants varying from 0.001 and 2 N/m are produced. The theoretical range of the resulting fundamental frequencies is approximately from 1 kHz to 15 kHz.

Official source

https://infoscience.epfl.ch/entities/publication/a59db884-a51a-4ef1-b41e-4b5f8d6c1823

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2006
Reports

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/a59db884-a51a-4ef1-b41e-4b5f8d6c1823

About this result

Related concepts (32)

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