Publications related to Proteome-wide prediction of the mode of inheritance and molecular mechanisms underlying genetic diseases using structural interactomics

Related publications (16)

Predicting Attention Deficits and Functional Recovery After Glioma Resection Through Functional Executive Networks: Insights From Dynamic Properties

BackgroundPostoperative short-term attentional and executive dysfunctions are common after brain tumor resection, significantly impacting patients' quality of life and functional recovery. This longitudinal cross-sectional study investigated whether presur ...

SPRINGER2025

Machine-Learning-Powered Neural Interfaces for Smart Prosthetics and Diagnostics

Mahsa Shoaran, Mohammad Ali Shaeri, Jinhan Liu

Advanced neural interfaces are transforming applications ranging from neuroscience research to diagnostic tools (for mental state recognition, tremor and seizure detection) as well as prosthetic devices (for motor and communication recovery). By integratin ...

Institute of Electrical and Electronics Engineers2025

Measurement - Based/Model-Less Estimation of Voltage Sensitivity Coefficients by Feedforward and LSTM Neural Networks in Power Distribution Grids

Rahul Kumar Gupta

The increasing adoption of measurement units in electrical power distribution grids has enabled the deployment of data-driven and measurement-based control schemes. Such schemes rely on measurement-based estimated models, where the models are first estimat ...

Institute of Electrical and Electronics Engineers Inc.2024

Deep learning approach for identification of H II regions during reionization in 21-cm observations - II. Foreground contamination

Jean-Paul Richard Kneib, Emma Elizabeth Tolley, Michele Bianco, Tianyue Chen

The upcoming Square Kilometre Array Observatory will produce images of neutral hydrogen distribution during the epoch of reionization by observing the corresponding 21-cm signal. However, the 21-cm signal will be subject to instrumental limitations such as ...

Oxford Univ Press2024

Decoding the brain: From neural representations to mechanistic models

Alexander Mathis, Mackenzie Mathis, Adriana Perez Rotondo

A central principle in neuroscience is that neurons within the brain act in concert to produce perception, cognition, and adaptive behavior. Neurons are organized into specialized brain areas, dedicated to different functions to varying extents, and their ...

CELL PRESS2024

Uncertainty quantification for Fisher-Kolmogorov equation on graphs with application to patient-specific Alzheimer's disease

Alfio Quarteroni

The Fisher-Kolmogorov equation is a diffusion-reaction PDE that models the accumulation of prionic proteins, which are responsible for many different neurological disorders. The most important and studied misfolded protein in literature is the Amyloid-beta ...

EDP SCIENCES S A2024

Optical data processing using structural non-linearity

Demetri Psaltis, Christophe Moser, Niyazi Ulas Dinç, Ilker Oguz, Mustafa Yildirim

A device (1) and method for processing data comprises at least one input layer (2), at least one modulation layer (3), and at least one output layer (4). The input layer (2) is configured to receive at least one carrier signal (Sc). The modulation layer (3 ...

2024

A Statistical Framework to Investigate the Optimality of Signal-Reconstruction Methods

Michaël Unser, Pakshal Narendra Bohra, Pol del Aguila Pla

We present a statistical framework to benchmark the performance of reconstruction algorithms for linear inverse problems, in particular, neural-network-based methods that require large quantities of training data. We generate synthetic signals as realizati ...

2023

Complex Representation Learning with Graph Convolutional Networks for Knowledge Graph Alignment

Quoc Viet Hung Nguyen, Thành Tâm Nguyên, Thanh Trung Huynh

The task of discovering equivalent entities in knowledge graphs (KGs), so-called KG entity alignment, has drawn much attention to overcome the incompleteness problem of KGs. The majority of existing techniques learns the pointwise representations of entiti ...

Wiley-Hindawi2023

Manifold Learning-Based Polynomial Chaos Expansions For High-Dimensional Surrogate Models

Ketson Roberto Maximiano Dos Santos

In this work we introduce a manifold learning-based method for uncertainty quantification (UQ) in systems describing complex spatiotemporal processes. Our first objective is to identify the embedding of a set of high-dimensional data representing quantitie ...

2022

Locality defeats the curse of dimensionality in convolutional teacher-student scenarios*

Matthieu Wyart, Alessandro Favero, Francesco Cagnetta

Convolutional neural networks perform a local and translationally-invariant treatment of the data: quantifying which of these two aspects is central to their success remains a challenge. We study this problem within a teacher-student framework for kernel r ...

IOP Publishing Ltd2022

Bayesian Recurrent Units and the Forward-Backward Algorithm

Philip Neil Garner

Using Bayes's theorem, we derive a unit-wise recurrence as well as a backward recursion similar to the forward-backward algorithm. The resulting Bayesian recurrent units can be integrated as recurrent neural networks within deep learning frameworks, while ...

ISCA-INT SPEECH COMMUNICATION ASSOC2022

Data-Driven Control and Its Applications to Microgrids

Alireza Karimi, Seyed Sohail Madani

Renewable energy resources have an increasing share of the electrical power, and the concept of distributed generation and storage units is about to completely change the basic architecture and control algorithms of the electric power grids. In this tutori ...

IEEE2022

Democratizing Machine Learning

Nirupam Gupta, Rafaël Benjamin Pinot, Alexandre David Olivier Maurer

The increasing prevalence of personal devices motivates the design of algorithms that can leverage their computing power, together with the data they generate, in order to build privacy-preserving and effective machine learning models. However, traditional ...

IEEE2022

Assessing and enhancing foldability in designed proteins

Bruno Emanuel Ferreira De Sousa Correia, Stéphane Rosset, Che Yang

Recent advances in protein-design methodology have led to a dramatic increase in reliability and scale. With these advances, dozens and even thousands of designed proteins are automatically generated and screened. Nevertheless, the success rate, particular ...

WILEY2022

Reduced representations of complexes, signals, and multifiltrations

Celia Camille Hacker

The field of computational topology has developed many powerful tools to describe the shape of data, offering an alternative point of view from classical statistics. This results in a variety of complex structures that are not always directly amenable for ...

EPFL2022