Publication

Modelling cell seeding to homogenize cell distribution within scaffold for tissue engineering

2015
Student Projects

Abstract

Cell Seeding is a key factor for good regeneration in tissue engineering. In order to ensure uniform tissue regeneration, a system has to be found to distribute cells evenly within the scaffold that will carry them in the body. In this extent, this work try to find an accurate description of compression forced induced suction which is a seeding technique with reported satisfying seeding efficiency. This description will take the form of a numerical model with COMSOL Multiphysics and will allow us to maximize the seeding in terms of homogeneity. In order to find the best possible seeding, strains and velocities of the compression will be further analyzed. The scaffold material properties will also be examined in order to have the best possible material for that kind of applications.

Official source

https://infoscience.epfl.ch/entities/publication/9f140665-dddc-4b82-b278-14c58b9c264a

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2015
Student Projects

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/9f140665-dddc-4b82-b278-14c58b9c264a

About this result

Related concepts (32)

Tissue engineering

Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biological tissues. Tissue engineering often involves the use of cells placed on tissue scaffolds in the formation of new viable tissue for a medical purpose but is not limited to applications involving cells and tissue scaffolds.

Cell culture

Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions. They need to be kept at body temperature (37 °C) in an incubator.

Data compression

In information theory, data compression, source coding, or bit-rate reduction is the process of encoding information using fewer bits than the original representation. Any particular compression is either lossy or lossless. Lossless compression reduces bits by identifying and eliminating statistical redundancy. No information is lost in lossless compression. Lossy compression reduces bits by removing unnecessary or less important information.

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